Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7787027 | 0.85 | EDNRA (0.53) | EDNRAEDNRB | |
| SCHEMBL1008387 | 0.85 | EDNRA (0.53) | EDNRAEDNRB | |
| SCHEMBL7793953 | 0.85 | EDNRA (0.64) | EDNRAEDNRB | |
| SCHEMBL2489314 | 0.85 | EDNRA (0.53) | EDNRAEDNRB | |
| SCHEMBL1009078 | 0.84 | EDNRA (0.66) | EDNRAEDNRB | |
| SCHEMBL8007885 | 0.84 | EDNRA (0.55) | EDNRAEDNRB | |
| SCHEMBL10066030 | 0.82 | EDNRA (0.52) | EDNRAEDNRB | |
| SCHEMBL2487362 | 0.82 | EDNRA (0.52) | EDNRAEDNRB | |
| SCHEMBL2492997 | 0.81 | EDNRA (0.50) | EDNRAEDNRB | |
| SCHEMBL2489880 | 0.81 | EDNRA (0.56) | EDNRAEDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2268634-A2 | PROCESSES FOR THE PREPARATION OF BOSENTAN AND RELATED COMPOUNDS USING NOVEL INTERMEDIATES | Actavis Group PTC EHF (IS) | 2011-01-05 | — | — | EP | disclosed |
| WO-2009112954-A2 | PROCESSES FOR THE PREPARATION OF BOSENTAN AND RELATED COMPOUNDS USING NOVEL INTERMEDIATES | ACTAVIS GROUP PTC EHF (IS) | 2009-09-17 | — | — | WO | disclosed |