Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 2/20 | 0.45 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.44 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.44 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.44 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.44 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.44 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.44 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.44 |
| ▸ | CD44 | P16070 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4604943 | 0.87 | AHR (0.47) | AHRCD44HPGDCYP2C19KDM4E | |
| SCHEMBL12054920 | 0.86 | AHR (0.60) | AHRPRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL19323001 | 0.77 | HPGD (0.45) | AHRPRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL21020816 | 0.77 | ALKBH3 (0.49) | AHRPRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL15340914 | 0.77 | CD44 (0.46) | AHRPRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL23908222 | 0.76 | TDP1 (0.47) | HPGDTDP1KDM4EMEN1ALDH1A1 | |
| SCHEMBL1047205 | 0.74 | TP53 (0.42) | AHRPRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL1045006 | 0.74 | AHR (0.57) | AHRTP53 | |
| SCHEMBL13494487 | 0.73 | CYP3A4 (0.48) | AHRHPGDCYP2D6CYP2C9ALOX15 | |
| SCHEMBL16168616 | 0.73 | AHR (0.46) | AHRHPGDCYP2D6CYP2C9ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120108823-A1 | ANTI-FRANCISELLA AGENTS | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2012-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120108823-A1 | ANTI-FRANCISELLA AGENTS | PTGS1, PTGS2, PTGES2 | AHR 4848/4885PRKAB2 853/4885PRKAG1 722/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.