Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 4/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA5A | P35218 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4100153 | 0.84 | TSHR (0.39) | TSHRKMT2AALDH1A1L3MBTL1MEN1 | |
| SCHEMBL1138697 | 0.83 | TSHR (0.65) | TSHRKMT2AALDH1A1MEN1MAPT | |
| SCHEMBL12532643 | 0.79 | TSHR (0.38) | TSHRKMT2AALDH1A1L3MBTL1MEN1 | |
| SCHEMBL12516240 | 0.75 | TSHR (0.40) | TSHRKMT2AALDH1A1L3MBTL1MEN1 | |
| SCHEMBL4308950 | 0.72 | KMT2A (0.75) | TSHRKMT2AALDH1A1L3MBTL1MEN1 | |
| SCHEMBL12517430 | 0.72 | KMT2A (0.39) | TSHRKMT2AALDH1A1L3MBTL1MEN1 | |
| SCHEMBL5073338 | 0.66 | TDP1 (0.37) | TSHRKMT2AALDH1A1L3MBTL1MEN1 | |
| SCHEMBL4325339 | 0.63 | TSHR (0.55) | TSHRKMT2AALDH1A1MEN1ESR1 | |
| SCHEMBL12516508 | 0.63 | TSHR (0.41) | TSHRKMT2AALDH1A1MEN1CYP3A4 | |
| SCHEMBL14753378 | 0.63 | ALDH1A1 (0.54) | TSHRKMT2AALDH1A1L3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8168725-B2 | Degradation of polypropylene with hydroxylamine ester compositions | BASF SE (DE) | 2012-05-01 | — | — | US | disclosed |
| US-20110207892-A1 | DEGRADATION OF POLYPROPYLENE WITH HYDROXYLAMINE ESTER COMPOSITIONS | ROTH MICHAEL | 2011-08-25 | — | — | US | disclosed |