Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.33 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10066154 | 0.84 | TSHR (0.42) | TSHRKMT2AL3MBTL1ALDH1A1TDP1 | |
| SCHEMBL1138697 | 0.79 | TSHR (0.65) | TSHRKMT2AALDH1A1TDP1MEN1 | |
| SCHEMBL7935169 | 0.79 | SLC6A2 (0.45) | TSHRKMT2ASLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL12532643 | 0.78 | TSHR (0.38) | TSHRKMT2AL3MBTL1ALDH1A1MEN1 | |
| SCHEMBL6754518 | 0.76 | SLC6A2 (0.45) | TSHRKMT2ASLC6A2SLC6A3HRH1 | |
| SCHEMBL4106868 | 0.74 | TSHR (0.67) | TSHRKMT2ASLC6A2SLC6A3L3MBTL1 | |
| SCHEMBL12516240 | 0.74 | TSHR (0.40) | TSHRKMT2AL3MBTL1ALDH1A1TDP1 | |
| SCHEMBL17287083 | 0.74 | SLC6A2 (0.50) | TSHRKMT2ASLC6A2SLC6A3HRH1 | |
| SCHEMBL562024 | 0.72 | SLC6A2 (0.45) | TSHRKMT2ASLC6A2SLC6A3HRH1 | |
| SCHEMBL4106959 | 0.72 | KMT2A (0.71) | TSHRKMT2ASLC6A2SLC6A3L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8168725-B2 | Degradation of polypropylene with hydroxylamine ester compositions | BASF SE (DE) | 2012-05-01 | — | — | US | disclosed |
| US-20110207892-A1 | DEGRADATION OF POLYPROPYLENE WITH HYDROXYLAMINE ESTER COMPOSITIONS | ROTH MICHAEL | 2011-08-25 | — | — | US | disclosed |