Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 16/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16168690 | 0.82 | DPP4 (0.40) | ALDH1A1RAB9ASMN1; SMN2ROCK2 | |
| SCHEMBL2713357 | 0.80 | LMNA (0.45) | ALDH1A1RAB9ASMN1; SMN2ROCK2 | |
| SCHEMBL2713361 | 0.80 | LMNA (0.45) | ALDH1A1RAB9ASMN1; SMN2ROCK2 | |
| Bromide SCHEMBL2711090 | 0.78 | LMNA (0.44) | ROCK2 | |
| Bromide SCHEMBL309082 | 0.78 | LMNA (0.44) | ROCK2 | |
| SCHEMBL10066180 | 0.71 | PDK1 (0.41) | RAB9ASMN1; SMN2 | |
| SCHEMBL23109923 | 0.70 | RAD52 (0.40) | ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL16168694 | 0.69 | DRD3 (0.49) | ROCK2 | |
| SCHEMBL13526379 | 0.69 | PDK1 (0.40) | RAB9ASMN1; SMN2 | |
| SCHEMBL13526371 | 0.69 | PDK1 (0.40) | ALDH1A1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012006203-A1 | N-CYCLYL-3 - (CYCLYLCARBONYLAMINOMETHYL) BENZAMIDE DERIVATIVES AS RHO KINASE INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-01-12 | — | — | WO | disclosed |