Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 5/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.40 |
| ▸ | CASP1 | P29466 | 2/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | BCL2 | P10415 | 4/20 | 0.36 |
| ▸ | BCL2L1 | Q07817 | 4/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12606797 | 0.86 | MCL1 (0.41) | MCL1FFAR1CASP1CNR2HTT | |
| SCHEMBL14364714 | 0.86 | HTT (0.38) | MCL1CASP1HTTSMN1; SMN2LMNA | |
| SCHEMBL13181443 | 0.86 | MCL1 (0.45) | MCL1CASP1HTTSMN1; SMN2MAPT | |
| SCHEMBL13243767 | 0.82 | HSD11B1 (0.37) | MCL1HTTSMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL12608155 | 0.82 | MAPT (0.46) | CNR2SMN1; SMN2GAAMAPTKDM4E | |
| SCHEMBL9915246 | 0.82 | FFAR1 (0.42) | MCL1FFAR1CASP1CNR2HTT | |
| SCHEMBL12608152 | 0.80 | HTT (0.43) | MCL1FFAR1CASP1CNR2HTT | |
| SCHEMBL13924246 | 0.79 | MAPT (0.39) | CNR2HTTSMN1; SMN2GAAMAPT | |
| SCHEMBL12807707 | 0.76 | HSD11B1 (0.36) | FFAR1CASP1CNR2PTPN1CNR1 | |
| SCHEMBL13266196 | 0.73 | HTT (0.46) | HTTSMN1; SMN2MAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8178590-B2 | Block copolymer and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-05-15 | — | — | US | disclosed |