Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 5/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 3/20 | 0.34 |
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.33 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14557898 | 0.84 | CASP1 (0.38) | HSD11B1PTPN1CASP1SCN9AEPAS1 | |
| SCHEMBL12807717 | 0.84 | HSD11B1 (0.36) | HSD11B1PTPN1CASP1MMP2MMP9 | |
| SCHEMBL12807706 | 0.81 | HSD11B1 (0.31) | HSD11B1CASP1 | |
| SCHEMBL12807699 | 0.80 | CASP1 (0.38) | HSD11B1PTPN1CASP1SCN9A | |
| SCHEMBL10296813 | 0.79 | HSD11B1 (0.34) | HSD11B1PTPN1CASP1MMP2MMP9 | |
| SCHEMBL10066817 | 0.76 | MCL1 (0.40) | PTPN1CASP1CNR2CNR1FFAR1 | |
| SCHEMBL15468153 | 0.76 | HSD11B1 (0.33) | HSD11B1PTPN1 | |
| SCHEMBL14545946 | 0.75 | HSD11B1 (0.34) | HSD11B1PTPN1CASP1MMP2MMP9 | |
| SCHEMBL19322855 | 0.75 | MAPT (0.42) | SLC6A4FFAR1 | |
| SCHEMBL14545945 | 0.75 | HSD11B1 (0.34) | HSD11B1PTPN1CASP1MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110081597-A1 | POLYMER ELECTROLYTE, CROSSLINKED POLYMER ELECTROLYTE, POLYMER ELECTROLYTE MEMBRANE AND USE OF THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-04-07 | — | — | US | disclosed |