Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22480307 | 0.92 | THRB (0.44) | ALDH1A1SMN1; SMN2TP53CYP3A4MAPK1 | |
| SCHEMBL22480288 | 0.92 | THRB (0.44) | ALDH1A1SMN1; SMN2TP53CYP3A4MAPK1 | |
| SCHEMBL22480299 | 0.89 | GLA (0.53) | ALDH1A1SMN1; SMN2GLAKMT2ALMNA | |
| SCHEMBL13485601 | 0.85 | ALDH1A1 (0.45) | ALDH1A1SMN1; SMN2TP53CYP3A4MAPK1 | |
| SCHEMBL22480295 | 0.84 | GLA (0.49) | ALDH1A1SMN1; SMN2GLAKMT2AMEN1 | |
| SCHEMBL13485598 | 0.82 | KMT2A (0.36) | ALDH1A1SMN1; SMN2TP53CYP3A4MAPK1 | |
| SCHEMBL13384333 | 0.82 | SMN1; SMN2 (0.47) | ALDH1A1SMN1; SMN2GLAKMT2ALMNA | |
| SCHEMBL16327978 | 0.81 | SMN1; SMN2 (0.46) | ALDH1A1SMN1; SMN2GLAKMT2AMEN1 | |
| SCHEMBL10066881 | 0.81 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2TP53CYP3A4MAPK1 | |
| SCHEMBL13485603 | 0.81 | THRB (0.42) | ALDH1A1SMN1; SMN2TP53CYP3A4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2121771-B2 | NOVEL RADIATION CURABLE COMPOSITIONS | AGFA GRAPHICS NV (BE) | 2016-12-07 | — | — | EP | disclosed |
| US-8338499-B2 | Amine co-initiators for radiation curable compositions | AGFA GRAPHICS NV (BE) | 2012-12-25 | — | — | US | disclosed |
| US-8338499-B2 | Amine co-initiators for radiation curable compositions | AGFA GRAPHICS NV (BE) | 2012-12-25 | — | — | US | disclosed |
| EP-2121771-B1 | NOVEL RADIATION CURABLE COMPOSITIONS | AGFA GRAPHICS NV (BE) | 2012-06-27 | — | — | EP | disclosed |
| US-20100041784-A1 | NOVEL RADIATION CURABLE COMPOSITIONS | AGFA GRAPHICS NV (BE) | 2010-02-18 | — | — | US | disclosed |
| US-20100041784-A1 | NOVEL RADIATION CURABLE COMPOSITIONS | AGFA GRAPHICS NV (BE) | 2010-02-18 | — | — | US | disclosed |
| WO-2008074758-A1 | NOVEL RADIATION CURABLE COMPOSITIONS | AGFA GRAPHICS NV (BE) | 2008-06-26 | — | — | WO | disclosed |