SCHEMBL10067565

SCHEMBL10067565

CCC(=O)Nc1ccccc1S(=O)(=O)O

nearest known ligand 0.53

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CA1 P00915 9/20 0.53
CA2 P00918 9/20 0.53
ALDH1A1 P00352 4/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
NPC1 O15118 1/20 0.48
RAB9A P51151 1/20 0.48
MAPT P10636 2/20 0.45
ATM Q13315 1/20 0.45
GAA P10253 1/20 0.45
HPGD P15428 3/20 0.44
KDM4E B2RXH2 1/20 0.44
LMNA P02545 1/20 0.44
HTT P42858 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
MAPK1 P28482 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3581670 0.85 CA1 (0.55) CA1CA2ALDH1A1SMN1; SMN2MAPT
SCHEMBL28232248 0.84 CA1 (0.54) CA1CA2SMN1; SMN2HTT
SCHEMBL29780051 0.83 CETP (0.59) SMN1; SMN2ATMLMNANPSR1
SCHEMBL9799462 0.83 CA1 (0.76) CA1CA2
SCHEMBL6362947 0.83 CA1 (0.53) CA1CA2SMN1; SMN2HTTMAPK1
SCHEMBL4138486 0.82 CETP (0.62) LMNANPSR1
SCHEMBL10035669 0.82 CETP (0.62) LMNANPSR1
SCHEMBL31612639 0.82 CETP (0.62) LMNANPSR1
SCHEMBL8619629 0.81 MAPK1 (0.60) ALDH1A1SMN1; SMN2NPC1RAB9AMAPT
SCHEMBL30673688 0.80 ALDH1A1 (0.55) CA1CA2ALDH1A1SMN1; SMN2HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8110329-B2 Charge controlling agent and toner CANON KABUSHIKI KAISHA (JP) 2012-02-07 US disclosed