Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 14/20 | 0.54 |
| ▸ | CA2 | P00918 | 14/20 | 0.54 |
| ▸ | CA4 | P22748 | 2/20 | 0.43 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | FABP4 | P15090 | 1/20 | 0.41 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9799462 | 0.84 | CA1 (0.76) | CA1CA2CA4 | |
| SCHEMBL10067565 | 0.84 | CA1 (0.53) | CA1CA2HTTSMN1; SMN2 | |
| SCHEMBL6362947 | 0.84 | CA1 (0.53) | CA1CA2CA4TTRFABP4 | |
| SCHEMBL10035670 | 0.83 | CA1 (0.49) | CA1CA2CA4HTTSMN1; SMN2 | |
| SCHEMBL3581670 | 0.83 | CA1 (0.55) | CA1CA2CA4HTTSMN1; SMN2 | |
| SCHEMBL10893116 | 0.81 | CA2 (0.54) | CA1CA2TTRFABP4CCNA2 | |
| SCHEMBL8901007 | 0.80 | RAB9A (0.60) | CA1CA2SMN1; SMN2 | |
| SCHEMBL7297478 | 0.79 | CA1 (0.50) | CA1CA2TTRFABP4CCNA2 | |
| Sulfuric Acid SCHEMBL21378339 | 0.79 | KDM1A (0.53) | CA1CA2HTTSMN1; SMN2 | |
| SCHEMBL27502345 | 0.78 | CA1 (0.49) | CA1CA2TTRFABP4CCNA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122094952-A | Pyrazolopyridine-based DNA-dependent protein kinase inhibitors and compositions and their use in gene editing | — | 2026-05-26 | — | — | CN | disclosed |
| CN-122094961-A | DNA-dependent protein kinase inhibitors and compositions based on 5, 6-core silacycle and their use in gene editing | — | 2026-05-26 | — | — | CN | disclosed |
| CN-119212978-A | Oxoindolinyl amide derivatives for inhibiting NLRP3 and use thereof | 万特斯治疗美国公司 | 2024-12-27 | — | — | CN | disclosed |
| CN-118891042-A | Viral helicase inhibitors binding to novel allosteric binding sites | 艾斯巴赫生物有限公司 | 2024-11-01 | — | — | CN | disclosed |
| CN-111655692-B | Nitrogen-containing heterocyclic amide compound and medical application thereof | 日本烟草产业株式会社 | 2023-10-10 | — | — | CN | disclosed |
| CN-114748622-A | P38 kinase inhibitors reduce DUX4 and downstream gene expression for the treatment of FSHD | 弗尔康医疗公司 | 2022-07-15 | — | — | CN | disclosed |
| CN-114732910-A | P38 kinase inhibitor reduces DUX4 and downstream gene expression for treatment of FSHD | 弗尔康医疗公司 | 2022-07-12 | — | — | CN | disclosed |
| CN-114716387-A | Prostate specific membrane antigen targeted high affinity agents for intracavitary radiotherapy of prostate cancer | 约翰霍普金斯大学 | 2022-07-08 | — | — | CN | disclosed |
| CN-111601593-B | P38 kinase inhibitor reduces DUX4 and downstream gene expression for treatment of FSHD | 弗尔康医疗公司 | 2022-04-15 | — | — | CN | disclosed |
| CN-109311827-B | Prostate specific membrane antigen targeted high affinity agents for intracavitary radiotherapy of prostate cancer | 约翰霍普金斯大学 | 2022-04-12 | — | — | CN | disclosed |
| CN-112689633-A | For inhibiting Nav1.8 pyridine carboxamide Compounds | 利伯研究所公司 | 2021-04-20 | — | — | CN | disclosed |
| CN-112689629-A | For inhibiting Nav1.8 pyridazine Compounds | 利伯研究所公司 | 2021-04-20 | — | — | CN | disclosed |
| CN-111601593-A | P38 kinase inhibitor reduces DUX4 and downstream gene expression for treatment of FSHD | 弗尔康医疗公司 | 2020-08-28 | — | — | CN | disclosed |
| CN-111032632-A | Prostate specific membrane antigen targeted high affinity agents for intracavitary radiotherapy of prostate cancer | 约翰霍普金斯大学 | 2020-04-17 | — | — | CN | disclosed |
| CN-108369612-A | Automated sample quality assessment | 梅塔博隆股份有限公司 | 2018-08-03 | — | — | CN | disclosed |