⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3167431 | 0.78 | ALDH1A1 (0.43) | — | |
| SCHEMBL31375385 | 0.78 | ALDH1A1 (0.43) | — | |
| SCHEMBL123243 | 0.74 | — | — | |
| SCHEMBL678538 | 0.74 | — | — | |
| SCHEMBL2465050 | 0.74 | — | — | |
| SCHEMBL444086 | 0.74 | — | — | |
| SCHEMBL3168192 | 0.74 | ALDH1A1 (0.40) | — | |
| SCHEMBL11700071 | 0.74 | — | — | |
| SCHEMBL7300417 | 0.74 | — | — | |
| SCHEMBL60147 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9803240-B2 | Stabilized nucleic acid dark quencher-fluorophore probes | BIOSEARCH TECHNOLOGIES, INC. (US) | 2017-10-31 | — | — | US | claimed |
| EP-2757091-B1 | Stabilized Nucleic Acid Dark Quencher-Fluorophore Probes | BIOSEARCH TECH INC (US) | 2017-06-28 | — | — | EP | claimed |
| EP-2757091-A1 | Stabilized Nucleic Acid Dark Quencher-Fluorophore Probes | Biosearch Technologies, Inc. (US) | 2014-07-23 | — | — | EP | claimed |
| US-20140194611-A1 | STABILIZED NUCLEIC ACID DARK QUENCHER-FLUOROPHORE PROBES | BIOSEARCH TECHNOLOGIES, INC. (US) | 2014-07-10 | — | — | US | claimed |
| CN-1660819-A | Ramification of N-carbethoxy cytosine and preparation method and application | DISAINO MEDICINE DEV CO LTD SH (CN) | 2005-08-31 | — | — | CN | claimed |
| US-6114520-A | ANTITUMOR AGENTS | HOFFMANN-LA ROCHE INC. (US) | 2000-09-05 | — | — | US | claimed |
| CN-111072734-B | Uridine derivative and method for preparing doxifluridine medicament by using same | 中国科学院昆明植物研究所 | 2023-04-07 | — | — | CN | disclosed |
| CN-111100172-B | Cytosidine derivative and method for preparing capecitabine medicine from same | 中国科学院昆明植物研究所 | 2023-03-17 | — | — | CN | disclosed |
| CN-111100172-A | Cytosidine derivative and method for preparing capecitabine medicine from same | 中国科学院昆明植物研究所 | 2020-05-05 | — | — | CN | disclosed |
| CN-111072734-A | Uridine derivative and method for preparing doxifluridine medicament by using same | 中国科学院昆明植物研究所 | 2020-04-28 | — | — | CN | disclosed |
| US-9803240-B2 | Stabilized nucleic acid dark quencher-fluorophore probes | BIOSEARCH TECHNOLOGIES, INC. (US) | 2017-10-31 | — | — | US | disclosed |
| EP-2757091-B1 | Stabilized Nucleic Acid Dark Quencher-Fluorophore Probes | BIOSEARCH TECH INC (US) | 2017-06-28 | — | — | EP | disclosed |
| EP-2029570-B1 | FUSED THIOPHENE DERIVATIVES AS KINASE INHIBITORS | UCB PHARMA SA (BE) | 2014-10-15 | — | — | EP | disclosed |
| WO-1999040099-A1 | 5'-DEOXYCYTIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 1999-08-12 | — | — | WO | disclosed |
| EP-0882734-A2 | 5'-Deoxy-cytidine derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1998-12-09 | — | — | EP | disclosed |
| US-5830653-A | ABILITY TO INHIBIT GENE EXPRESSION | GILEAD SCIENCES, INC. (US) | 1998-11-03 | — | — | US | disclosed |
| US-5645985-A | USED FOR DIAGNOSIS TO DETECT VIRUSES OR DISEASED CONDITIONS | GILEAD SCIENCES, INC. (US) | 1997-07-08 | — | — | US | disclosed |
| EP-0637965-A4 | ENHANCED TRIPLE-HELIX AND DOUBLE-HELIX FORMATION WITH OLIGOMERS CONTAINING MODIFIED PYRIMIDINES. | GILEAD SCIENCES INC (US) | 1996-01-24 | — | — | EP | disclosed |
| EP-0637965-A1 | ENHANCED TRIPLE-HELIX AND DOUBLE-HELIX FORMATION WITH OLIGOMERS CONTAINING MODIFIED PYRIMIDINES | GILEAD SCIENCES, INC. (US) | 1995-02-15 | — | — | EP | disclosed |
| WO-1993010820-A1 | ENHANCED TRIPLE-HELIX AND DOUBLE-HELIX FORMATION WITH OLIGOMERS CONTAINING MODIFIED PYRIMIDINES | GILEAD SCIENCES, INC. (US) | 1993-06-10 | — | — | WO | disclosed |