⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31375385 | 0.83 | ALDH1A1 (0.43) | — | |
| SCHEMBL3167431 | 0.78 | ALDH1A1 (0.43) | — | |
| SCHEMBL2465050 | 0.74 | — | — | |
| SCHEMBL11700071 | 0.74 | — | — | |
| SCHEMBL1006770 | 0.74 | — | — | |
| SCHEMBL444086 | 0.74 | — | — | |
| SCHEMBL123243 | 0.74 | — | — | |
| SCHEMBL3168192 | 0.74 | ALDH1A1 (0.40) | — | |
| SCHEMBL7300417 | 0.74 | — | — | |
| SCHEMBL60147 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4357466-A | FROM A TOSYLATED DERIVATIVE | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1982-11-02 | — | — | US | claimed |
| JP-56068698-A | — | — | None | — | — | JP | disclosed |
| JP-56147797-A | — | — | None | — | — | JP | disclosed |
| US-8299035-B2 | 10a-azalide compound having 4-membered ring structure | TAISHO PHARMACEUTUCAL CO., LTD. (JP) | 2012-10-30 | — | — | US | disclosed |
| US-20110269717-A1 | NEUROGENESIS BY MODULATING ANGIOTENSIN | BRAINCELLS INC. (US) | 2011-11-03 | — | — | US | disclosed |
| US-20110152239-A1 | 10A-AZALIDE COMPOUND HAVING 4-MEMBERED RING STRUCTURE | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2011-06-23 | — | — | US | disclosed |
| US-20110046090-A1 | MODULATION OF NEUROGENESIS WITH GABA AGENTS AND GABA ANALOGS | BRAINCELLS INC. (US) | 2011-02-24 | — | — | US | disclosed |
| EP-2287173-A1 | 10A-AZALIDE COMPOUND HAVING 4-MEMBERED RING STRUCTURE | Taisho Pharmaceutical Co., Ltd. (JP) | 2011-02-23 | — | — | EP | disclosed |
| WO-2010111136-A2 | ALISKIREN MODULATION OF NEUROGENESIS | BRAINCELLS, INC. (US) | 2010-09-30 | — | — | WO | disclosed |
| US-7786079-B2 | Substituted nonadepsipeptides | AICURIS GMBH & CO. KG. (DE) | 2010-08-31 | — | — | US | disclosed |
| US-5621106-A | REACTING WITH DIALKYLTIN OXIDE; ACYLATION; ALKYLATION | TORONTO RESEARCH CHEMICALS, INC. (CA) | 1997-04-15 | — | — | US | disclosed |
| EP-0733630-A1 | NUCLEOSIDE DERIVATIVE | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1996-09-25 | — | — | EP | disclosed |
| US-5466809-A | From aminomannose, antitumor agents, castanospermine | TORONTO RESEARCH CHEMICALS, INC. (CA) | 1995-11-14 | — | — | US | disclosed |
| US-5432263-A | Process for producing peptides with side chains containing imidazolinylamino, tetrahydropyrimidinylamino, or alkylguanidinyl groups | ABBOTT LABORATORIES (US) | 1995-07-11 | — | — | US | disclosed |
| EP-0613478-A1 | IMMUNOSTIMULATING SWAINSONINE ANALOGS | TORONTO RESEARCH CHEMICALS INC. (CA) | 1994-09-07 | — | — | EP | disclosed |
| WO-1993009117-A1 | IMMUNOSTIMULATING SWAINSONINE ANALOGS | TORONTO RESEARCH CHEMICALS INC. (CA) | 1993-05-13 | — | — | WO | disclosed |
| EP-0103445-A2 | Process for production of prostaglandins E or F, and novel 7-(thiocarbo-acyloxy) prostaglandins E or F | TEIJIN LIMITED (JP) | 1984-03-21 | — | — | EP | disclosed |
| US-4357466-A | FROM A TOSYLATED DERIVATIVE | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1982-11-02 | — | — | US | disclosed |
| JP-S56147797-A | NEW PREPARATION OF 3\"-DEOXYDIHYDRO STREPTOMYCIN | MICROBIAL CHEM RES FOUND | 1981-11-16 | — | — | JP | disclosed |
| JP-S5668698-A | NEW PREPARATION OF 3'-DEOXYKANAMYCIN A | MICROBIAL CHEM RES FOUND | 1981-06-09 | — | — | JP | disclosed |