SCHEMBL1006776

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL9654573	0.87	KEAP1 (0.45)	KEAP1MMP2ALDH1A1TDP1HSD17B10
	SCHEMBL27866235	0.83	PARP1 (0.43)	KEAP1MMP2ALDH1A1HSD17B10KDM4E
	SCHEMBL7628578	0.82	KEAP1 (0.41)	KEAP1MMP2ALDH1A1KDM4EKMT2A
	SCHEMBL27819480	0.81	KEAP1 (0.59)	KEAP1MMP2ALDH1A1TDP1HSD17B10
	SCHEMBL1888280	0.81	KEAP1 (0.59)	KEAP1MMP2ALDH1A1TDP1HSD17B10
	Hydrochloric Acid SCHEMBL9064648	0.79	KEAP1 (0.57)	KEAP1MMP2ALDH1A1TDP1HSD17B10
	SCHEMBL21750061	0.79	KEAP1 (0.57)	KEAP1MMP2ALDH1A1TDP1HSD17B10
	SCHEMBL2791251	0.78	AKR1C2 (0.58)	KEAP1ALDH1A1TDP1HSD17B10AKR1C2
	SCHEMBL30692478	0.78	MMP2 (0.52)	KEAP1MMP2ALDH1A1TDP1HSD17B10
	SCHEMBL2192034	0.78	TDP1 (0.63)	KEAP1MMP2ALDH1A1TDP1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.