SCHEMBL1006781

SCHEMBL1006781

CC(=O)OC1CCC(C)OC1=O

nearest known ligand 0.39

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TAS2R46 P59540 2/20 0.39
TSHR P16473 1/20 0.37
CA1 P00915 1/20 0.36
CA9 Q16790 1/20 0.36
OPRK1 P41145 6/20 0.35
POLB P06746 2/20 0.35
MMP3 P08254 1/20 0.33
ALDH1A1 P00352 1/20 0.33
MAPK1 P28482 1/20 0.33
ESR1 P03372 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15722234 0.83 TSHR (0.42) TAS2R46TSHROPRK1POLBALDH1A1
SCHEMBL13126806 0.83 TSHR (0.42) TAS2R46TSHROPRK1POLBALDH1A1
SCHEMBL12705156 0.80 CA1 (0.32) CA1CA9POLBMMP3
SCHEMBL685961 0.78 CA1 (0.32) CA1CA9
SCHEMBL12750211 0.77 OPRK1 (0.38) TAS2R46OPRK1POLBALDH1A1
SCHEMBL12750213 0.77 OPRK1 (0.38) TAS2R46OPRK1POLBALDH1A1
SCHEMBL12750217 0.77 OPRK1 (0.38) TAS2R46OPRK1POLBALDH1A1
SCHEMBL3799178 0.75 ALDH1A1 (0.37) TSHRMMP3ALDH1A1MAPK1
SCHEMBL1005689 0.75 OPRK1 (0.47) TAS2R46TSHROPRK1ALDH1A1
SCHEMBL687003 0.74 CA1 (0.32) CA1CA9ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2268701-B1 CARBOHYDRATE LACTONE POLYMERS IMP INNOVATIONS LTD (GB) 2015-08-19 EP disclosed
EP-2268701-B1 CARBOHYDRATE LACTONE POLYMERS IMP INNOVATIONS LTD (GB) 2015-08-19 EP disclosed
US-8476402-B2 Carbohydrate lactone polymers IMPERIAL INNOVATIONS LIMITED (GB) 2013-07-02 US disclosed
US-8476402-B2 Carbohydrate lactone polymers IMPERIAL INNOVATIONS LIMITED (GB) 2013-07-02 US disclosed
US-8476402-B2 Carbohydrate lactone polymers IMPERIAL INNOVATIONS LIMITED (GB) 2013-07-02 US disclosed
US-20110077380-A1 CARBOHYDRATE LACTONE POLYMERS IMPERIAL INNOVATIONS LIMITED (GB) 2011-03-31 US disclosed
US-20110077380-A1 CARBOHYDRATE LACTONE POLYMERS IMPERIAL INNOVATIONS LIMITED (GB) 2011-03-31 US disclosed
US-20110077380-A1 CARBOHYDRATE LACTONE POLYMERS IMPERIAL INNOVATIONS LIMITED (GB) 2011-03-31 US disclosed
EP-2268701-A2 CARBOHYDRATE LACTONE POLYMERS Imperial Innovations Limited (GB) 2011-01-05 EP disclosed
WO-2009118538-A2 CARBOHYDRATE LACTONE POLYMERS IMPERIAL INNOVATIONS LIMITED (GB) 2009-10-01 WO disclosed
WO-2009118538-A2 CARBOHYDRATE LACTONE POLYMERS IMPERIAL INNOVATIONS LIMITED (GB) 2009-10-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110077380-A1 CARBOHYDRATE LACTONE POLYMERS MGAM, AGL, DDOST TAS2R46 2994/4885TSHR 4553/4885CA1 314/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.