Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | SYK | P43405 | 1/20 | 0.41 |
| ▸ | GSK3A | P49840 | 3/20 | 0.41 |
| ▸ | GSK3B | P49841 | 3/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | PRKX | P51817 | 1/20 | 0.41 |
| ▸ | PRKG1 | Q13976 | 1/20 | 0.41 |
| ▸ | MAPKAPK5 | Q8IW41 | 1/20 | 0.41 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.41 |
| ▸ | GBA1 | P04062 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ACVR1 | Q04771 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10068151 | 0.91 | HTT (0.54) | EPHX1SMN1; SMN2HTTRAB9ANPC1 | |
| SCHEMBL10068140 | 0.89 | EPHX1 (0.53) | EPHX1SMN1; SMN2HTTRAB9ANPC1 | |
| SCHEMBL10082138 | 0.89 | EPHX1 (0.47) | EPHX1SMN1; SMN2HTTMAPTRAB9A | |
| SCHEMBL10068162 | 0.85 | PIK3CG (0.45) | SMN1; SMN2HTTMAPTRAB9AMEN1 | |
| SCHEMBL10068163 | 0.84 | MAPK13 (0.57) | EPHX1SMN1; SMN2MAPTRAB9ANPC1 | |
| SCHEMBL10068168 | 0.81 | FPR2 (0.49) | SMN1; SMN2MAPTRAB9ANPC1KMT2A | |
| SCHEMBL10068149 | 0.81 | MAPK13 (0.55) | SMN1; SMN2HTTMAPTRAB9ANPC1 | |
| SCHEMBL22822777 | 0.80 | RAB9A (0.50) | SMN1; SMN2MAPTRAB9ANPC1MEN1 | |
| SCHEMBL77605 | 0.79 | ADORA3 (0.47) | SMN1; SMN2RAB9ANPC1TP53 | |
| SCHEMBL10082882 | 0.79 | CHRNB2 (0.52) | EPHX1SMN1; SMN2HTTMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8119646-B2 | Fungicide hydroximoyl-tetrazole derivatives | BAYER CROPSCIENCE AG (DE) | 2012-02-21 | — | — | US | disclosed |
| US-20090258875-A1 | Fungicide Hydroximoyl-Tetrazole Derivatives | BAYER CROPSCIENCE AG (DE) | 2009-10-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090258875-A1 | Fungicide Hydroximoyl-Tetrazole Derivatives | HAAO, CYP51A1, CYP8B1 | EPHX1 1280/4885SMN1; SMN2 4458/4885HTT 148/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.