Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AADAT | Q8N5Z0 | 3/20 | 0.49 |
| ▸ | KYAT1 | Q16773 | 1/20 | 0.49 |
| ▸ | KYAT3 | Q6YP21 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10067493 | 0.87 | AADAT (0.46) | AADATKYAT1KYAT3XIAP | |
| SCHEMBL6763281 | 0.81 | AADAT (0.74) | AADATKYAT1KYAT3 | |
| SCHEMBL9886291 | 0.76 | AADAT (0.47) | AADATKYAT1KYAT3LMNAMEN1 | |
| SCHEMBL10067844 | 0.73 | AADAT (0.43) | AADATKYAT1KYAT3MAPTALDH1A1 | |
| SCHEMBL3769896 | 0.72 | AADAT (0.64) | AADATKYAT1KYAT3 | |
| SCHEMBL9886290 | 0.71 | AADAT (0.43) | AADATKYAT1KYAT3GAAXIAP | |
| SCHEMBL3774766 | 0.70 | AADAT (0.67) | AADATKYAT1KYAT3 | |
| SCHEMBL3771910 | 0.70 | AADAT (0.67) | AADATKYAT1KYAT3 | |
| SCHEMBL9109650 | 0.69 | FFAR4 (0.35) | AADATKYAT1KYAT3LMNAPOLB | |
| SCHEMBL9886293 | 0.69 | KDM1A (0.38) | AADATKYAT1KYAT3LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8487104-B2 | KAT II inhibitors | PFIZER INC. (US) | 2013-07-16 | — | — | US | disclosed |
| US-20120142729-A1 | KAT ll INHIBITORS | PFIZER INC. | 2012-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120142729-A1 | KAT ll INHIBITORS | KAT7, KAT2A, KATNA1 | AADAT 1043/4885KYAT1 46/4885KYAT3 90/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.