Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.52 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.52 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | NPY1R | P25929 | 1/20 | 0.48 |
| ▸ | NPY2R | P49146 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HPGDS | O60760 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10068462 | 0.84 | ADRB2 (0.57) | ALDH1A1KDM4EADRB2ADRB1ADRB3 | |
| SCHEMBL10037333 | 0.83 | ALDH1A1 (0.64) | ALDH1A1KDM4ETDP1RAB9ANPC1 | |
| SCHEMBL27106380 | 0.82 | ALDH1A1 (0.68) | ALDH1A1KDM4ERAB9ANPC1POLB | |
| SCHEMBL14301138 | 0.82 | ALDH1A1 (0.71) | ALDH1A1KDM4ERAB9ANPC1POLB | |
| SCHEMBL3098211 | 0.79 | ALDH1A1 (1.00) | ALDH1A1KDM4ERAB9ANPC1POLB | |
| SCHEMBL3931641 | 0.78 | ALDH1A1 (0.61) | ALDH1A1TDP1RAB9ANPC1POLB | |
| Hydrochloric Acid SCHEMBL6822031 | 0.77 | ALDH1A1 (0.97) | ALDH1A1KDM4ERAB9ANPC1POLB | |
| SCHEMBL29660311 | 0.77 | ALDH1A1 (0.64) | ALDH1A1KDM4ERAB9ANPC1PTPN1 | |
| SCHEMBL16492740 | 0.77 | ALDH1A1 (0.64) | ALDH1A1KDM4ETDP1PTPN1MAPT | |
| SCHEMBL2104811 | 0.77 | ALDH1A1 (0.73) | ALDH1A1KDM4ERAB9ANPC1PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120077711-A1 | Novel Ligands and Libraries of Ligands | SUNESIS PHARMACEUTICALS, INC. (US) | 2012-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120077711-A1 | Novel Ligands and Libraries of Ligands | LSS, ABCG2, SELL | ALDH1A1 533/4885KDM4E 4640/4885ADRB2 706/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.