Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 16/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | IDH1 | O75874 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26449823 | 0.82 | GRM5 (0.42) | GRM5PDE10A | |
| SCHEMBL412937 | 0.81 | GRM5 (0.41) | GRM5PDE10ASCN9ASCN10A | |
| SCHEMBL25093234 | 0.78 | HRH3 (0.42) | GRM5PDE10A | |
| SCHEMBL27142767 | 0.76 | L3MBTL1 (0.41) | GRM5 | |
| SCHEMBL12427186 | 0.75 | CRBN (0.53) | GRM5SCN9APIM1 | |
| SCHEMBL469807 | 0.72 | CNR2 (0.52) | PIM1IDH1 | |
| SCHEMBL29348968 | 0.72 | GRM5 (0.42) | GRM5 | |
| SCHEMBL17419033 | 0.72 | GRM5 (0.40) | GRM5 | |
| SCHEMBL13424162 | 0.71 | IDH1 (0.38) | GRM5PIM1IDH1 | |
| SCHEMBL16360902 | 0.69 | HTR3A (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012033952-A1 | 3 - PHENYL- 2 -OXO- 1, 3 -OXAZOLIDINES FOR TREATMENT OF BACTERIAL INFECTIONS | MICURX PHARMACEUTICALS, INC. (KY) | 2012-03-15 | — | — | WO | disclosed |