Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDO2 | P48775 | 1/20 | 0.41 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | CETP | P11597 | 3/20 | 0.32 |
| ▸ | CALML3 | P27482 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 4/20 | 0.31 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.31 |
| ▸ | MAOB | P27338 | 2/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.30 |
| ▸ | GRM5 | P41594 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL412646 | 0.93 | TDO2 (0.42) | TDO2CETPCALML3MAOAMAOB | |
| SCHEMBL469913 | 0.87 | CALML3 (0.44) | TDO2CALML3MAOAMAOBCYP2C9 | |
| SCHEMBL10068630 | 0.85 | TDO2 (0.42) | TDO2CETPCALML3MAOAMAOB | |
| SCHEMBL412829 | 0.81 | CALML3 (0.53) | CALML3MAOAMAOBCYP2C9CYP2C19 | |
| SCHEMBL412791 | 0.80 | GRM5 (0.36) | CNR2CALML3MAOAMAOBCYP2C9 | |
| SCHEMBL412753 | 0.80 | CALML3 (0.48) | TDO2CALML3MAOAMAOBCYP2C9 | |
| SCHEMBL412640 | 0.79 | TDO2 (0.43) | TDO2CALML3MAOAMAOBCYP2C9 | |
| SCHEMBL412794 | 0.79 | TDO2 (0.46) | TDO2CALML3MAOAMAOBCYP2C9 | |
| SCHEMBL411159 | 0.79 | TDO2 (0.39) | TDO2CALML3MAOAMAOBCYP2C9 | |
| SCHEMBL411080 | 0.78 | TDO2 (0.40) | TDO2CALML3MAOAMAOBCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012033952-A1 | 3 - PHENYL- 2 -OXO- 1, 3 -OXAZOLIDINES FOR TREATMENT OF BACTERIAL INFECTIONS | MICURX PHARMACEUTICALS, INC. (KY) | 2012-03-15 | — | — | WO | disclosed |