Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP15 | Q460N3 | 4/20 | 0.49 |
| ▸ | PARP10 | Q53GL7 | 4/20 | 0.49 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10068810 | 0.94 | NR1H4 (0.50) | PARP15PARP10PARP2HSD17B10F2 | |
| SCHEMBL14813011 | 0.92 | WDR5 (0.48) | PARP15PARP10PARP2HSD17B10F2 | |
| SCHEMBL30056075 | 0.91 | KAT6A (0.52) | PARP15PARP10PARP2HSD17B10F2 | |
| SCHEMBL21817404 | 0.91 | KAT6A (0.52) | PARP15PARP10PARP2HSD17B10F2 | |
| SCHEMBL14164999 | 0.90 | PARP15 (0.47) | PARP15PARP10PARP2HSD17B10F2 | |
| SCHEMBL16396797 | 0.90 | NOTUM (0.46) | PARP15PARP10PARP2HSD17B10F2 | |
| SCHEMBL10068795 | 0.88 | WDR5 (0.44) | PARP15PARP10PARP2HSD17B10F2 | |
| SCHEMBL10068819 | 0.87 | ALDH1A1 (0.43) | PARP15PARP10PARP2HSD17B10F2 | |
| SCHEMBL21819200 | 0.87 | WDR5 (0.43) | PARP15PARP10PARP2HSD17B10F2 | |
| SCHEMBL23206842 | 0.86 | PARP15 (0.48) | PARP15PARP10PARP2F2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012019428-A1 | BENZOHYDROL DERIVATIVES, A PREPARATION PROCESS AND PHARMACEUTICAL USE THEREOF | 上海恒瑞医药有限公司 (CN) | 2012-02-16 | — | — | WO | disclosed |