Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 10/20 | 0.52 |
| ▸ | CTSK | P43235 | 10/20 | 0.52 |
| ▸ | CTSL | P07711 | 5/20 | 0.39 |
| ▸ | CTSB | P07858 | 4/20 | 0.39 |
| ▸ | CTSD | P07339 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.37 |
| ▸ | CTSH | P09668 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14151799 | 0.90 | CTSK (0.61) | CTSSCTSKCTSLCTSBKMT2A | |
| SCHEMBL14151800 | 0.90 | CTSK (0.61) | CTSSCTSKCTSLCTSBKMT2A | |
| SCHEMBL19744842 | 0.81 | CTSK (0.47) | CTSSCTSKCTSLCTSBKMT2A | |
| SCHEMBL16773 | 0.78 | CTSS (0.57) | CTSSCTSKCTSLCTSBKMT2A | |
| SCHEMBL970178 | 0.78 | CTSK (0.45) | CTSSCTSKCTSLCTSBCTSD | |
| SCHEMBL16774 | 0.78 | CTSS (0.57) | CTSSCTSKCTSLCTSBKMT2A | |
| SCHEMBL970179 | 0.78 | CTSK (0.45) | CTSSCTSKCTSLCTSBCTSD | |
| SCHEMBL16800 | 0.77 | CTSK (0.53) | CTSSCTSKCTSLKMT2AAAK1 | |
| SCHEMBL2199576 | 0.77 | CTSK (0.53) | CTSSCTSKCTSLKMT2AAAK1 | |
| SCHEMBL971301 | 0.77 | CTSK (0.51) | CTSSCTSKCTSLCTSBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012019428-A1 | BENZOHYDROL DERIVATIVES, A PREPARATION PROCESS AND PHARMACEUTICAL USE THEREOF | 上海恒瑞医药有限公司 (CN) | 2012-02-16 | — | — | WO | disclosed |