Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.60 |
| ▸ | CA1 | P00915 | 1/20 | 0.60 |
| ▸ | CA2 | P00918 | 1/20 | 0.60 |
| ▸ | CA9 | Q16790 | 1/20 | 0.60 |
| ▸ | CNR1 | P21554 | 2/20 | 0.58 |
| ▸ | MTOR | P42345 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.53 |
| ▸ | MEN1 | O00255 | 7/20 | 0.53 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 9/20 | 0.53 |
| ▸ | NPC1 | O15118 | 7/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | XBP1 | P17861 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10069138 | 0.83 | CA12 (0.60) | CA12CA1CA2CA9CNR1 | |
| SCHEMBL21133085 | 0.82 | MEN1 (0.78) | KMT2AMEN1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL31078919 | 0.81 | BAZ1A (0.69) | CA12CA1CA2CA9CNR1 | |
| SCHEMBL10069070 | 0.81 | ALDH1A1 (0.72) | CA12CA1CA2CA9KMT2A | |
| SCHEMBL30995905 | 0.80 | CA12 (0.60) | CA12CA1CA2CA9CNR1 | |
| SCHEMBL12218028 | 0.80 | CA12 (0.60) | CA12CA1CA2CA9CNR1 | |
| SCHEMBL11007034 | 0.80 | MEN1 (0.79) | CA12CA1CA2CA9CNR1 | |
| SCHEMBL11056635 | 0.80 | SMN1; SMN2 (0.74) | KMT2AMEN1TAAR1RAB9ANPC1 | |
| SCHEMBL3070329 | 0.80 | KMT2A (0.76) | CA12CA1CA2CA9KMT2A | |
| SCHEMBL4920556 | 0.79 | HPSE (0.72) | CA12CA1CA2CA9CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012021963-A1 | NOVEL SULFONAMIDE COMPOUNDS FOR INHIBITION OF METASTATIC TUMOR GROWTH | METASIGNAL THERAPEUTICS INC. (CA) | 2012-02-23 | — | — | WO | disclosed |