SCHEMBL10069152

SCHEMBL10069152

CC(C)COC(=O)C(CC(C)(C)C)C(C)(C)C

nearest known ligand 0.39

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.39
ALDH1A1 P00352 1/20 0.36
MMP8 P22894 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9056604 0.86 MAPK1 (0.39) TSHR
SCHEMBL22810806 0.82
SCHEMBL14748186 0.82 TSHR (0.45) TSHRALDH1A1MMP8SMN1; SMN2
SCHEMBL13367617 0.81 CA12 (0.37) ALDH1A1MMP8
SCHEMBL19222797 0.80 TSHR (0.39) TSHRALDH1A1MMP8SMN1; SMN2
SCHEMBL24951262 0.79 KDM4E (0.40)
SCHEMBL22619278 0.79
SCHEMBL1785987 0.79 TSHR (0.42) TSHRALDH1A1MMP8SMN1; SMN2
SCHEMBL10069151 0.79 ALDH1A1 (0.39) ALDH1A1MMP8
SCHEMBL14410327 0.79 ALDH1A1 (0.39) ALDH1A1MMP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11351509-B2 Filter with seal treatment TAIWAN SEMICONDUCTOR MANUFACTURING COMPANY, LTD. (TW) 2022-06-07 US disclosed
US-20200172650-A1 PHOTOSTABLE COMPOSITIONS COMPRISING PARA-ALKOXYL PHENYL SUBSTITUTED PROPENOIC ACID (APP) COPOLYMER DERIVATIVES BANK OF AMERICA, N.A., AS ADMINISTRATIVE AGENT 2020-06-04 US disclosed
US-9761449-B2 Gap filling materials and methods TAIWAN SEMICONDUCTOR MANUFACTURING COMPANY, LTD. (TW) 2017-09-12 US disclosed
EP-2423748-B1 Lithographic printing plate precursor and plate making method thereof FUJIFILM CORP (JP) 2013-05-22 EP disclosed
EP-2565714-A1 Lithographic printing plate precursor and method of preparing lithographic printing plate using the same Fujifilm Corporation (JP) 2013-03-06 EP disclosed
EP-2423748-A1 Lithographic printing plate precursor and plate making method thereof Fujifilm Corporation (JP) 2012-02-29 EP disclosed
US-20070122741-A1 Resist protective coating material and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2007-05-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200172650-A1 PHOTOSTABLE COMPOSITIONS COMPRISING PARA-ALKOXYL PHENYL SUBSTITUTED PROPENOIC ACID (APP) COPOLYMER DERIVATIVES APP, FAP, ANXA5 TSHR 3902/4885ALDH1A1 518/4885MMP8 4414/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.