Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 10/20 | 0.54 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.52 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | FAP | Q12884 | 1/20 | 0.44 |
| ▸ | PITRM1 | Q5JRX3 | 1/20 | 0.44 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.44 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.44 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2623068 | 0.81 | DPP4 (0.61) | DPP4FAPPITRM1DPP8DPP9 | |
| SCHEMBL255570 | 0.80 | DPP4 (0.49) | DPP4SLC22A2SLC47A1MAPTALDH1A1 | |
| SCHEMBL23460047 | 0.80 | DPP4 (0.49) | DPP4SLC22A2SLC47A1MAPTALDH1A1 | |
| SCHEMBL18397921 | 0.80 | ALDH1A1 (0.50) | DPP4SLC22A2SLC47A1MAPTALDH1A1 | |
| SCHEMBL6739912 | 0.80 | DPP4 (0.49) | DPP4SLC22A2SLC47A1MAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL28561377 | 0.78 | ALDH1A1 (0.50) | DPP4SLC22A2SLC47A1MAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL28561376 | 0.78 | ALDH1A1 (0.50) | DPP4SLC22A2SLC47A1MAPTALDH1A1 | |
| SCHEMBL15535092 | 0.78 | DPP4 (0.51) | DPP4SLC22A2SLC47A1MAPTALDH1A1 | |
| SCHEMBL15149731 | 0.78 | DPP4 (0.51) | DPP4SLC22A2SLC47A1MAPTALDH1A1 | |
| SCHEMBL8073575 | 0.76 | ALDH1A1 (0.50) | DPP4SLC22A2SLC47A1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012021876-A2 | PEPTIDOMIMETIC MACROCYCLES | AILERON THERAPEUTICS, INC. (US) | 2012-02-16 | — | — | WO | disclosed |