Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 2/20 | 0.61 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.52 |
| ▸ | TPH1 | P17752 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ALPI | P09923 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | XIAP | P98170 | 1/20 | 0.50 |
| ▸ | DPP4 | P27487 | 2/20 | 0.49 |
| ▸ | ACACB | O00763 | 1/20 | 0.49 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.47 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL157002 | 0.86 | SLC7A5 (0.69) | ANPEPENPEPALDH1A1SLC7A5TPH1 | |
| SCHEMBL93441 | 0.86 | SLC7A5 (0.69) | ANPEPENPEPALDH1A1SLC7A5TPH1 | |
| SCHEMBL18067341 | 0.86 | KMT2A (0.57) | ANPEPENPEPALDH1A1SLC7A5TPH1 | |
| SCHEMBL19295504 | 0.86 | SLC7A5 (0.69) | ANPEPENPEPALDH1A1SLC7A5TPH1 | |
| SCHEMBL3203962 | 0.86 | TPH1 (0.49) | ANPEPENPEPALDH1A1SLC7A5TPH1 | |
| Hydrochloric Acid SCHEMBL6708183 | 0.85 | SLC7A5 (0.67) | ANPEPENPEPALDH1A1SLC7A5TPH1 | |
| Hydrochloric Acid SCHEMBL6708181 | 0.85 | SLC7A5 (0.67) | ANPEPENPEPALDH1A1SLC7A5TPH1 | |
| Hydrochloric Acid SCHEMBL27479092 | 0.85 | SLC7A5 (0.67) | ANPEPENPEPALDH1A1SLC7A5TPH1 | |
| SCHEMBL16728148 | 0.84 | SLC7A5 (0.55) | ALDH1A1SLC7A5TPH1ALPIPKM | |
| SCHEMBL5183224 | 0.82 | ANPEP (0.62) | ANPEPENPEPALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024059472-A1 | MACROCYCLIC IMMUNOMODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-03-21 | — | — | WO | disclosed |
| WO-2012021876-A2 | PEPTIDOMIMETIC MACROCYCLES | AILERON THERAPEUTICS, INC. (US) | 2012-02-16 | — | — | WO | disclosed |