Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPH1 | P17752 | 1/20 | 0.49 |
| ▸ | SLC7A5 | Q01650 | 3/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.47 |
| ▸ | ALPI | P09923 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | XIAP | P98170 | 1/20 | 0.47 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.45 |
| ▸ | ANPEP | P15144 | 1/20 | 0.44 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CSK | P41240 | 1/20 | 0.41 |
| ▸ | GRB2 | P62993 | 1/20 | 0.41 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16728148 | 0.93 | SLC7A5 (0.55) | TPH1SLC7A5PTGS1ALPIPKM | |
| SCHEMBL18067341 | 0.88 | KMT2A (0.57) | TPH1SLC7A5PTGS1ALPIPKM | |
| SCHEMBL10069256 | 0.86 | ANPEP (0.61) | TPH1SLC7A5PTGS1ALPIPKM | |
| SCHEMBL20714851 | 0.83 | PRSS1 (0.50) | TPH1SLC7A5PTGS1ALPIPKM | |
| SCHEMBL4672949 | 0.82 | SLC7A5 (0.50) | TPH1SLC7A5PTGS1ALPIPKM | |
| SCHEMBL13696626 | 0.82 | SLC7A5 (0.50) | TPH1SLC7A5PTGS1ALPIPKM | |
| SCHEMBL2603687 | 0.82 | SLC7A5 (0.71) | SLC7A5PTGS1ALPIPKMXIAP | |
| SCHEMBL8279093 | 0.82 | SLC7A5 (0.71) | SLC7A5PTGS1ALPIPKMXIAP | |
| SCHEMBL12285673 | 0.82 | SLC7A5 (0.71) | SLC7A5PTGS1ALPIPKMXIAP | |
| SCHEMBL14387733 | 0.82 | SLC7A5 (0.50) | TPH1SLC7A5PTGS1ALPIPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100068783-A1 | TAILORED CONTROL OF SURFACE PROPERTIES BY CHEMICAL MODIFICATION | ISIS INNOVATION LIMITED (GB) | 2010-03-18 | — | — | US | claimed |
| EP-2054465-A1 | TAILORED CONTROL OF SURFACE PROPERTIES BY CHEMICAL MODIFICATION | ISIS INNOVATION LIMITED (GB) | 2009-05-06 | — | — | EP | claimed |
| WO-2008023170-A1 | TAILORED CONTROL OF SURFACE PROPERTIES BY CHEMICAL MODIFICATION | ISIS INNOVATION LIMITED (GB) | 2008-02-28 | — | — | WO | claimed |
| US-8530212-B2 | Carbene precursor compound for producing an adhesive surface on a substrate | ISIS INNOVATION LIMITED (GB) | 2013-09-10 | — | — | US | disclosed |
| US-20100068783-A1 | TAILORED CONTROL OF SURFACE PROPERTIES BY CHEMICAL MODIFICATION | ISIS INNOVATION LIMITED (GB) | 2010-03-18 | — | — | US | disclosed |
| EP-2054465-A1 | TAILORED CONTROL OF SURFACE PROPERTIES BY CHEMICAL MODIFICATION | ISIS INNOVATION LIMITED (GB) | 2009-05-06 | — | — | EP | disclosed |
| WO-2008023170-A1 | TAILORED CONTROL OF SURFACE PROPERTIES BY CHEMICAL MODIFICATION | ISIS INNOVATION LIMITED (GB) | 2008-02-28 | — | — | WO | disclosed |
| US-6979566-B2 | Method of treatment of viral infection including HIV using water soluble fullerenes—III | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2005-12-27 | — | — | US | disclosed |
| US-20040044062-A1 | Method of treatment of viral infection including HIV using water soluble fullerenes - III | FRIEDMAN SIMON H (US) | 2004-03-04 | — | — | US | disclosed |
| US-6613771-B2 | Prevent human retroviral reproduction, infections | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2003-09-02 | — | — | US | disclosed |
| US-20010041801-A1 | Water soluble fullerenes with antiviral activity | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2001-11-15 | — | — | US | disclosed |
| US-6204391-B1 | PREVENT REPRODUCTION OF HUMAN RETROVIRUSES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2001-03-20 | — | — | US | disclosed |
| WO-1995019949-A1 | WATER SOLUBLE FULLERENES WITH ANTIVIRAL ACTIVITY | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1995-07-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040044062-A1 | Method of treatment of viral infection including HIV using water soluble fullerenes - III | CD4, RPP30, CASP3 | TPH1 2387/4885SLC7A5 2233/4885PTGS1 3455/4885 |
| US-20100068783-A1 | TAILORED CONTROL OF SURFACE PROPERTIES BY CHEMICAL MODIFICATION | ITGB2, ITGA2B, ITGB1 | TPH1 1468/4885SLC7A5 3107/4885PTGS1 2653/4885 |
| US-20010041801-A1 | Water soluble fullerenes with antiviral activity | ZC3HAV1, RPL35, SARS1 | TPH1 3235/4885SLC7A5 1390/4885PTGS1 3202/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.