Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.47 |
| ▸ | LMNA | P02545 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | HRH2 | P25021 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10069369 | 0.93 | KDM4E (0.44) | KDM4ELMNAALDH1A1SMN1; SMN2POLB | |
| SCHEMBL10068784 | 0.90 | MEN1 (0.39) | LMNAALDH1A1SMN1; SMN2TSHRHTT | |
| SCHEMBL10068767 | 0.89 | FAAH (0.43) | ALDH1A1SMN1; SMN2MAPTKMT2AADRB3 | |
| SCHEMBL10068952 | 0.89 | HTT (0.38) | LMNAALDH1A1SMN1; SMN2TSHRHTT | |
| SCHEMBL10068721 | 0.89 | HTT (0.40) | LMNAALDH1A1SMN1; SMN2TSHRHTT | |
| SCHEMBL10069328 | 0.88 | ADRB3 (0.42) | LMNASMN1; SMN2TSHRHTTCYP1A2 | |
| SCHEMBL10068561 | 0.88 | TSHR (0.45) | LMNASMN1; SMN2TSHRHTTCYP1A2 | |
| SCHEMBL10068546 | 0.86 | HTT (0.36) | LMNASMN1; SMN2TSHRHTTCYP1A2 | |
| SCHEMBL2027362 | 0.86 | HTT (0.43) | LMNASMN1; SMN2TSHRHTTCYP1A2 | |
| SCHEMBL10068584 | 0.85 | SMN1; SMN2 (0.38) | LMNASMN1; SMN2TSHRHTTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012019428-A1 | BENZOHYDROL DERIVATIVES, A PREPARATION PROCESS AND PHARMACEUTICAL USE THEREOF | 上海恒瑞医药有限公司 (CN) | 2012-02-16 | — | — | WO | disclosed |