Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 17/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29766853 | 0.83 | F2R (1.00) | F2RKMT2A | |
| SCHEMBL882467 | 0.83 | F2R (1.00) | F2RKMT2A | |
| SCHEMBL18025116 | 0.81 | F2R (0.82) | F2RALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL10069459 | 0.81 | KMT2A (0.66) | F2RKMT2ASMN1; SMN2 | |
| SCHEMBL882783 | 0.77 | F2R (0.70) | F2RALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL10069453 | 0.76 | F2R (0.71) | F2RMAPTLMNASMN1; SMN2 | |
| SCHEMBL882468 | 0.76 | F2R (0.85) | F2RALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL19308454 | 0.76 | AR (0.60) | F2RALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL27473596 | 0.72 | MEN1 (0.69) | ALDH1A1HPGDKMT2ASMN1; SMN2 | |
| SCHEMBL10069461 | 0.72 | F2R (1.00) | F2RALDH1A1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9422262-B2 | Compounds and methods for treating diseases mediated by protease activated receptors | THE BROAD INSTITUTE, INC. (US) | 2016-08-23 | — | — | US | disclosed |
| US-9422262-B2 | Compounds and methods for treating diseases mediated by protease activated receptors | THE BROAD INSTITUTE, INC. (US) | 2016-08-23 | — | — | US | disclosed |
| WO-2012040636-A2 | COMPOUNDS AND METHODS FOR TREATING DISEASES MEDIATED BY PROTEASE ACTIVATED RECEPTORS | THE BROAD INSTITUTE, INC. (US) | 2012-03-29 | — | — | WO | disclosed |