SCHEMBL10069637

SCHEMBL10069637

C=C(C)C(=O)CCNc1cc(S(=O)(=O)O)cc2cc(S(=O)(=O)O)c(/N=N/c3ccc4ccccc4c3S(=O)(=O)O)c(O)c12

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CYP1A2 P05177 4/20 0.51
▸ MAPK1 P28482 2/20 0.51
▸ CYP2C9 P11712 2/20 0.51
▸ DNASE1L3 Q13609 1/20 0.51
▸ ENPP2 Q13822 6/20 0.46
▸ PHLPP2 Q6ZVD8 2/20 0.44
▸ FUT8 Q9BYC5 1/20 0.44
▸ ALDH1A1 P00352 2/20 0.43
▸ HIF1A Q16665 2/20 0.43
▸ MEN1 O00255 2/20 0.42
▸ KMT2A Q03164 2/20 0.42
▸ HTT P42858 1/20 0.42
▸ PRMT1 Q99873 1/20 0.42
▸ THRB P10828 1/20 0.41
▸ TDP1 Q9NUW8 1/20 0.41
▸ TSHR P16473 1/20 0.40
▸ PTPRA P18433 1/20 0.40
▸ PTPRB P23467 1/20 0.40
▸ CYP2C19 P33261 1/20 0.40
▸ RAPGEF4 Q8WZA2 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10039849 0.90 ALDH1A1 (0.40) CYP1A2MAPK1CYP2C9DNASE1L3ENPP2
SCHEMBL8779889 0.85 CYP1A2 (0.54) CYP1A2MAPK1CYP2C9DNASE1L3ENPP2
SCHEMBL11307037 0.82 CYP1A2 (0.54) CYP1A2MAPK1CYP2C9DNASE1L3ENPP2
SCHEMBL8779895 0.82 CYP1A2 (0.54) CYP1A2MAPK1CYP2C9DNASE1L3ENPP2
SCHEMBL8779910 0.81 CYP1A2 (0.55) CYP1A2MAPK1CYP2C9DNASE1L3ENPP2
SCHEMBL8779919 0.81 CYP1A2 (0.51) CYP1A2MAPK1CYP2C9DNASE1L3ENPP2
SCHEMBL8779896 0.80 CYP1A2 (0.49) CYP1A2MAPK1CYP2C9DNASE1L3ENPP2
SCHEMBL13763562 0.80 CYP1A2 (0.64) CYP1A2MAPK1CYP2C9DNASE1L3ENPP2
SCHEMBL8779869 0.79 CYP1A2 (0.49) CYP1A2MAPK1CYP2C9DNASE1L3ENPP2
SCHEMBL6028562 0.78 PHLPP2 (0.65) CYP1A2MAPK1CYP2C9DNASE1L3ENPP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10435566-B2 Particles for electrophoretic displays MERCK PATENT GMBH (DE) 2019-10-08 — — US disclosed
EP-3233944-B1 PARTICLES FOR ELECTROPHORETIC DISPLAYS MERCK PATENT GMBH (DE) 2019-09-04 — — EP disclosed
EP-2577392-B1 COLOURED POLYMER PARTICLES MERCK PATENT GMBH (DE) 2019-06-26 — — EP disclosed
EP-2393849-B1 COLOURED PARTICLES FOR ELECTROPHORETIC DISPLAYS MERCK PATENT GMBH (DE) 2019-06-19 — — EP disclosed
EP-2393851-B1 COLOURED PARTICLES FOR ELECTROPHORETIC DISPLAYS MERCK PATENT GMBH (DE) 2018-02-28 — — EP disclosed
US-20180037744-A1 PARTICLES FOR ELECTROPHORETIC DISPLAYS E INK CORPORATION 2018-02-08 — — US disclosed
WO-2016096091-A1 PARTICLES FOR ELECTROPHORETIC DISPLAYS MERCK PATENT GMBH (DE) 2016-06-23 — — WO disclosed
US-9115464-B2 Particles for electrophoretic displays MERCK PATENT GMBH (DE) 2015-08-25 — — US disclosed
US-8743451-B2 Coloured particles for electrophoretic displays MERCK PATENT GMBH (DE) 2014-06-03 — — US disclosed
US-20120041165-A1 PARTICLES FOR ELECTROPHORETIC DISPLAYS MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) 2012-02-16 — — US disclosed
US-20110297888-A1 COLOURED PARTICLES FOR ELECTROPHORETIC DISPLAYS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2011-12-08 — — US disclosed
WO-2010089057-A2 PARTICLES FOR ELECTROPHORETIC DISPLAYS MERCK PATENT GMBH (DE) 2010-08-12 — — WO disclosed
WO-2010089060-A2 PARTICLES FOR ELECTROPHORETIC DISPLAYS MERCK PATENT GMBH (DE) 2010-08-12 — — WO disclosed
WO-2010089059-A1 COLOURED PARTICLES FOR ELECTROPHORETIC DISPLAYS MERCK PATENT GMBH (DE) 2010-08-12 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180037744-A1 PARTICLES FOR ELECTROPHORETIC DISPLAYS RAB5IF, GYPA, SELP CYP1A2 4479/4885MAPK1 4178/4885CYP2C9 4264/4885
US-10435566-B2 Particles for electrophoretic displays RAB5IF, SELP, SELE CYP1A2 4592/4885MAPK1 4352/4885CYP2C9 4500/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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