Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | EEF2K | O00418 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 3/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TNKS | O95271 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10069660 | 0.92 | MAPT (0.46) | KDM4EEEF2KALDH1A1MAPTTP53 | |
| SCHEMBL23332276 | 0.86 | KDM4E (0.50) | KDM4EEEF2KALDH1A1ALDH2MAOB | |
| SCHEMBL10069664 | 0.85 | KDM4E (0.40) | KDM4EALDH1A1MAPTTP53SMN1; SMN2 | |
| SCHEMBL10069658 | 0.85 | MAP2K3 (0.52) | KDM4EALDH1A1MAPTMAOBCYP19A1 | |
| SCHEMBL10069667 | 0.83 | KDM4E (0.46) | KDM4EEEF2KALDH1A1MAPTTP53 | |
| SCHEMBL6146093 | 0.80 | KDM4E (0.59) | KDM4EEEF2KALDH1A1ALDH2MAOB | |
| SCHEMBL12121778 | 0.80 | KDM4E (0.59) | KDM4EEEF2KALDH1A1ALDH2MAOB | |
| SCHEMBL6146090 | 0.80 | KDM4E (0.59) | KDM4EEEF2KALDH1A1ALDH2MAOB | |
| SCHEMBL10069659 | 0.79 | ALDH1A1 (0.44) | KDM4EALDH1A1MAPTTP53SMN1; SMN2 | |
| SCHEMBL5612911 | 0.76 | KDM4E (0.55) | KDM4EEEF2KALDH1A1ALDH2KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012016619-A1 | PHENETHYL, PHENETHYLENE, PHENETHYNE AND INDANONE DERIVATES IN COSMETIC FORMULATIONS, ESPECIALLY FOR USE IN SKIN AGEING PROCESSES | MERCK PATENT GMBH (DE) | 2012-02-09 | — | — | WO | disclosed |