Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.72 |
| ▸ | VCP | P55072 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.57 |
| ▸ | CES2 | O00748 | 1/20 | 0.56 |
| ▸ | CES1 | P23141 | 1/20 | 0.56 |
| ▸ | BCHE | P06276 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.50 |
| ▸ | RELA | Q04206 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10069798 | 0.93 | APP (0.72) | APPVCPNPC1RAB9AMEN1 | |
| SCHEMBL10069794 | 0.91 | APP (0.84) | APPVCPNPC1RAB9AMEN1 | |
| SCHEMBL9193189 | 0.89 | FFAR1 (0.60) | APPNPC1RAB9APOLBNFKB1 | |
| SCHEMBL28695966 | 0.85 | APP (0.75) | APPVCPNPC1RAB9ACES2 | |
| SCHEMBL27167232 | 0.85 | APP (0.75) | APPVCPNPC1RAB9ACES2 | |
| SCHEMBL28629549 | 0.84 | APP (0.73) | APPVCPCES2CES1 | |
| SCHEMBL10170737 | 0.84 | APP (0.73) | APPVCPCES2CES1 | |
| SCHEMBL28972914 | 0.84 | APP (0.73) | APPVCPRAB9ACES2CES1 | |
| SCHEMBL28972824 | 0.84 | APP (0.73) | APPVCPNPC1RAB9AMEN1 | |
| SCHEMBL6241316 | 0.83 | NPC1 (0.65) | APPVCPNPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250186408-A1 | TREATMENT OF PHARMACORESISTANT EPILEPSY | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2025-06-12 | — | — | US | disclosed |
| CN-116354914-B | Triphenylsubstituted pyrone derivative and synthetic method and application thereof | 河南科技大学 | 2024-09-03 | — | — | CN | disclosed |
| EP-4333819-A1 | TREATMENT OF PHARMACORESISTANT EPILEPSY | Katholieke Universiteit Leuven (BE) | 2024-03-13 | — | — | EP | disclosed |
| CN-116354914-A | Triphenylsubstituted pyrone derivative and synthetic method and application thereof | 河南科技大学 | 2023-06-30 | — | — | CN | disclosed |
| WO-2022233877-A1 | TREATMENT OF PHARMACORESISTANT EPILEPSY | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2022-11-10 | — | — | WO | disclosed |
| CN-108997362-B | Pyranoindolone fused cyclic derivative and synthesis method and application thereof | 华东师范大学 | 2021-07-27 | — | — | CN | disclosed |
| CN-109810147-B | Pyrene-labeled benzimidazole nitrogen heterocyclic carbene palladium metal complex, and preparation and application thereof | 中国科学院兰州化学物理研究所 | 2021-02-26 | — | — | CN | disclosed |
| WO-2012016619-A1 | PHENETHYL, PHENETHYLENE, PHENETHYNE AND INDANONE DERIVATES IN COSMETIC FORMULATIONS, ESPECIALLY FOR USE IN SKIN AGEING PROCESSES | MERCK PATENT GMBH (DE) | 2012-02-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250186408-A1 | TREATMENT OF PHARMACORESISTANT EPILEPSY | CNR1, CNR2, CYP2J2 | APP 1233/4885VCP 4323/4885NPC1 2657/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.