Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 5/20 | 0.73 |
| ▸ | GPR183 | P32249 | 2/20 | 0.54 |
| ▸ | VCP | P55072 | 1/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10170737 | 1.00 | APP (0.73) | APPGPR183VCPNFE2L2CES2 | |
| SCHEMBL10069794 | 0.92 | APP (0.84) | APPVCPCES2CES1 | |
| SCHEMBL30114875 | 0.87 | APP (0.75) | APPGPR183VCPCES2CES1 | |
| SCHEMBL27167232 | 0.86 | APP (0.75) | APPVCPCES2CES1 | |
| SCHEMBL28695966 | 0.86 | APP (0.75) | APPVCPCES2CES1 | |
| SCHEMBL28972824 | 0.84 | APP (0.73) | APPGPR183VCPCES2CES1 | |
| SCHEMBL28972914 | 0.84 | APP (0.73) | APPVCPCES2CES1 | |
| SCHEMBL10069797 | 0.84 | APP (0.72) | APPVCPCES2CES1 | |
| SCHEMBL10069798 | 0.84 | APP (0.72) | APPVCPCES2CES1 | |
| SCHEMBL28972867 | 0.84 | APP (0.68) | APPGPR183 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115677739-A | Preparation method of O, O-boron difluoride complex | 华南理工大学 | 2023-02-03 | — | — | CN | disclosed |
| CN-113429280-B | Method for preparing chalcone compounds by selective hydrogenation reduction of alkynone under catalysis of Ti (III) complex | 陕西师范大学 | 2022-08-23 | — | — | CN | disclosed |
| CN-110452270-B | Azacarbene palladium complex crystal, synthesis method thereof and application thereof in preparation of alpha, beta-unsaturated ketone compound | 陕西师范大学 | 2022-02-25 | — | — | CN | disclosed |
| CN-113429280-A | Method for preparing chalcone compounds by selective hydrogenation reduction of alkynone under catalysis of Ti (III) complex | 陕西师范大学 | 2021-09-24 | — | — | CN | disclosed |