Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 4/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | DRD5 | P21918 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8329871 | 0.80 | KDM1A (0.66) | KDM1AHTR2AHTR2CHTR2BRCOR1 | |
| SCHEMBL15372957 | 0.80 | KDM1A (0.66) | KDM1AHTR2AHTR2CHTR2BRCOR1 | |
| SCHEMBL15084369 | 0.78 | KDM1A (0.37) | KDM1AHTR2AHTR2CHTR2BROCK2 | |
| SCHEMBL679857 | 0.77 | MAOA (0.47) | KDM1AHTR2CRCOR1DRD3 | |
| SCHEMBL17948233 | 0.77 | MAOA (0.47) | KDM1AHTR2CRCOR1DRD3 | |
| SCHEMBL14330231 | 0.77 | MAOA (0.47) | KDM1AHTR2CRCOR1DRD3 | |
| SCHEMBL15084368 | 0.77 | MAOA (0.47) | KDM1AHTR2CRCOR1DRD3 | |
| SCHEMBL13484227 | 0.77 | MAOA (0.47) | KDM1AHTR2CRCOR1DRD3 | |
| SCHEMBL684465 | 0.77 | MAOA (0.47) | KDM1AHTR2CRCOR1DRD3 | |
| SCHEMBL19385073 | 0.76 | KDM1A (0.50) | KDM1AHTR2AHTR2CHTR2BRCOR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012006202-A1 | RHO KINASE INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-01-12 | — | — | WO | disclosed |