Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 5/20 | 0.66 |
| ▸ | HTR2A | P28223 | 5/20 | 0.56 |
| ▸ | HTR2C | P28335 | 5/20 | 0.56 |
| ▸ | HTR2B | P41595 | 5/20 | 0.56 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD5 | P21918 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15372957 | 1.00 | KDM1A (0.66) | KDM1AHTR2AHTR2CHTR2BRCOR1 | |
| SCHEMBL25513836 | 0.81 | KDM1A (0.53) | KDM1AHTR2AHTR2CHTR2BRCOR1 | |
| SCHEMBL10069996 | 0.80 | KDM1A (0.51) | KDM1AHTR2AHTR2CHTR2BRCOR1 | |
| SCHEMBL8329869 | 0.79 | KDM1A (0.66) | KDM1AHTR2AHTR2CHTR2BRCOR1 | |
| SCHEMBL20187237 | 0.79 | KDM1A (1.00) | KDM1AHTR2AHTR2CHTR2BRCOR1 | |
| SCHEMBL15096161 | 0.79 | KDM1A (1.00) | KDM1AHTR2AHTR2CHTR2BRCOR1 | |
| SCHEMBL25606213 | 0.78 | KDM1A (0.54) | KDM1AHTR2AHTR2CHTR2BHRH3 | |
| Hydrochloric Acid SCHEMBL16340510 | 0.78 | KDM1A (1.00) | KDM1AHTR2AHTR2CHTR2BRCOR1 | |
| Hydrochloric Acid SCHEMBL17766516 | 0.78 | KDM1A (1.00) | KDM1AHTR2AHTR2CHTR2BRCOR1 | |
| SCHEMBL22849885 | 0.78 | KDM1A (0.53) | KDM1AHTR2AHTR2CHTR2BRCOR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011021645-A1 | BICYCLIC UREA DERIVATIVE OR PHARMACOLOGICALLY PERMITTED SALT THEREOF | 大日本住友製薬株式会社 (JP) | 2011-02-24 | — | — | WO | disclosed |
| US-5889031-A | CONTROLLING CIRCADIAN RHYTHMS | BRISTOL-MYERS SQUIBB COMPNAY (US) | 1999-03-30 | — | — | US | disclosed |