Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10070426 | 0.87 | ALDH1A1 (0.35) | ALDH1A1TLR7 | |
| SCHEMBL10071008 | 0.86 | ALDH1A1 (0.33) | MMP1MMP9MMP13ALDH1A1TLR7 | |
| SCHEMBL10069920 | 0.86 | PDE4B (0.40) | MMP1MMP9MMP13 | |
| SCHEMBL10070422 | 0.85 | TLR7 (0.31) | TLR7 | |
| SCHEMBL10070428 | 0.83 | — | — | |
| SCHEMBL10069879 | 0.83 | TYK2 (0.32) | TLR7 | |
| SCHEMBL10070933 | 0.81 | — | — | |
| SCHEMBL10070926 | 0.80 | PIK3C3 (0.31) | MMP1MMP9MMP13 | |
| SCHEMBL10070043 | 0.79 | TSHR (0.35) | ALDH1A1TLR7 | |
| SCHEMBL10069877 | 0.79 | THRA (0.34) | TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012006680-A1 | 7, 9-NITROGEN RADICAL-4-OXO-4H-PYRIDO[L,2-A]PYRIMIDINE-2-CARBOXYLIC ACID BENZYLAMIDE ANTI-VIRALS | AVEXA LIMITED (AU) | 2012-01-19 | — | — | WO | disclosed |