SCHEMBL10070201

SCHEMBL10070201

CC(C)c1ccc(CCC(=O)c2ccccc2)cc1

nearest known ligand 0.60

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 4/20 0.60
USP5 P45974 1/20 0.60
ALDH1A1 P00352 1/20 0.60
RAB9A P51151 5/20 0.57
NPC1 O15118 4/20 0.55
TDP1 Q9NUW8 2/20 0.54
CASP3 P42574 1/20 0.54
SENP8 Q96LD8 1/20 0.54
SENP7 Q9BQF6 1/20 0.54
SENP6 Q9GZR1 1/20 0.54
SMN1; SMN2 Q16637 1/20 0.51
FKBP1A P62942 1/20 0.48
EPHX1 P07099 1/20 0.48
SIGMAR1 Q99720 1/20 0.48
LMNA P02545 1/20 0.47
MAPT P10636 1/20 0.47
NR4A2 P43354 1/20 0.47
FFAR1 O14842 1/20 0.47
ABCB1 P08183 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10070199 0.93 USP5 (0.65) L3MBTL1USP5ALDH1A1RAB9ANPC1
SCHEMBL10070197 0.91 USP5 (0.66) L3MBTL1USP5ALDH1A1RAB9ANPC1
SCHEMBL10178695 0.86 RAB9A (0.51) L3MBTL1USP5ALDH1A1RAB9ANPC1
SCHEMBL24648965 0.83 POLB (0.62) L3MBTL1USP5ALDH1A1RAB9ANPC1
SCHEMBL3917034 0.83 NPC1 (0.56) L3MBTL1USP5ALDH1A1RAB9ANPC1
SCHEMBL10070207 0.83 RAB9A (0.68) L3MBTL1USP5ALDH1A1RAB9ANPC1
SCHEMBL10070206 0.83 RAB9A (0.68) L3MBTL1USP5ALDH1A1RAB9ANPC1
SCHEMBL16178566 0.82 NPC1 (0.53) L3MBTL1ALDH1A1RAB9ANPC1TDP1
SCHEMBL15524969 0.82 TDP1 (0.77) L3MBTL1ALDH1A1RAB9ANPC1TDP1
SCHEMBL28251466 0.82 TDP1 (0.77) L3MBTL1ALDH1A1RAB9ANPC1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106478395-B A kind of method of iridium catalyzed synthesizing alpha-alkyl ketone 南京理工大学 2019-06-25 CN disclosed
CN-106478325-B A method of synthesis alpha-alkyl ketone 南京理工大学 2019-06-25 CN disclosed
CN-106478395-A A kind of method of iridium catalyzed synthesizing alpha-alkyl ketone 南京理工大学 2017-03-08 CN disclosed
CN-106478325-A A kind of method of synthesis alpha-alkyl ketone 南京理工大学 2017-03-08 CN disclosed
WO-2012016619-A1 PHENETHYL, PHENETHYLENE, PHENETHYNE AND INDANONE DERIVATES IN COSMETIC FORMULATIONS, ESPECIALLY FOR USE IN SKIN AGEING PROCESSES MERCK PATENT GMBH (DE) 2012-02-09 WO disclosed
EP-1096916-B1 METHOD FOR PROVIDING DIBENZOYLMETHANE DERIVATIVES WITH LIGHT STABILITY OREAL (FR) 2009-08-19 EP disclosed