Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP5 | P45974 | 1/20 | 0.65 |
| ▸ | RAB9A | P51151 | 4/20 | 0.64 |
| ▸ | NPC1 | O15118 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | CASP3 | P42574 | 1/20 | 0.54 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.54 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.54 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.52 |
| ▸ | DPP4 | P27487 | 1/20 | 0.51 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.51 |
| ▸ | PDE4A | P27815 | 1/20 | 0.50 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.50 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10070201 | 0.93 | L3MBTL1 (0.60) | USP5RAB9ANPC1ALDH1A1L3MBTL1 | |
| SCHEMBL10070197 | 0.91 | USP5 (0.66) | USP5RAB9ANPC1ALDH1A1L3MBTL1 | |
| SCHEMBL8118437 | 0.85 | USP5 (0.72) | USP5RAB9ANPC1ALDH1A1L3MBTL1 | |
| Phenyl Propionic Acid SCHEMBL6567856 | 0.84 | KEAP1 (0.59) | USP5RAB9ANPC1ALDH1A1L3MBTL1 | |
| SCHEMBL10070207 | 0.83 | RAB9A (0.68) | USP5RAB9ANPC1ALDH1A1L3MBTL1 | |
| SCHEMBL10070206 | 0.83 | RAB9A (0.68) | USP5RAB9ANPC1ALDH1A1L3MBTL1 | |
| SCHEMBL28251466 | 0.82 | TDP1 (0.77) | RAB9ANPC1ALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL30572 | 0.82 | TDP1 (0.77) | RAB9ANPC1ALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL30089581 | 0.82 | USP5 (0.85) | USP5RAB9ANPC1ALDH1A1L3MBTL1 | |
| SCHEMBL15524969 | 0.82 | TDP1 (0.77) | RAB9ANPC1ALDH1A1L3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012016619-A1 | PHENETHYL, PHENETHYLENE, PHENETHYNE AND INDANONE DERIVATES IN COSMETIC FORMULATIONS, ESPECIALLY FOR USE IN SKIN AGEING PROCESSES | MERCK PATENT GMBH (DE) | 2012-02-09 | — | — | WO | disclosed |