Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.32 |
| ▸ | LCK | P06239 | 1/20 | 0.31 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.31 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | MTOR | P42345 | 1/20 | 0.30 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
| ▸ | MMP9 | P14780 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10071002 | 0.92 | TSHR (0.36) | HPGDMAPTTSHRTAAR1HSD17B10 | |
| SCHEMBL15101327 | 0.89 | MAPT (0.35) | HPGDMAPTTSHRTAAR1HSD17B10 | |
| SCHEMBL10070043 | 0.82 | TSHR (0.35) | HPGDMAPTTSHRTAAR1HSD17B10 | |
| SCHEMBL10070052 | 0.81 | TSHR (0.35) | HPGDMAPTTSHRTAAR1HSD17B10 | |
| SCHEMBL10070064 | 0.81 | HPGD (0.35) | HPGDMAPTTSHRTAAR1HSD17B10 | |
| SCHEMBL10070425 | 0.81 | SYK (0.40) | HPGDMAPTTSHRTAAR1HSD17B10 | |
| SCHEMBL10070066 | 0.81 | MAPT (0.37) | HPGDMAPTHSD17B10KDM4EALDH1A1 | |
| SCHEMBL10070068 | 0.80 | HSD17B10 (0.35) | HPGDMAPTTSHRTAAR1HSD17B10 | |
| SCHEMBL10069878 | 0.80 | HPGD (0.35) | HPGDMAPTTSHRTAAR1HSD17B10 | |
| SCHEMBL15101373 | 0.80 | MET (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012006680-A1 | 7, 9-NITROGEN RADICAL-4-OXO-4H-PYRIDO[L,2-A]PYRIMIDINE-2-CARBOXYLIC ACID BENZYLAMIDE ANTI-VIRALS | AVEXA LIMITED (AU) | 2012-01-19 | — | — | WO | disclosed |