Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.31 |
| ▸ | LCK | P06239 | 1/20 | 0.30 |
| ▸ | SRC | P12931 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10070429 | 0.92 | HPGD (0.35) | TSHRHSD17B10MAPTHPGDTAAR1 | |
| SCHEMBL10070942 | 0.80 | HSD17B10 (0.36) | TSHRHSD17B10MAPTHPGDTAAR1 | |
| SCHEMBL10070392 | 0.79 | TLR7 (0.30) | — | |
| SCHEMBL10070414 | 0.75 | CNR2 (0.39) | CNR2TP53KMT2A | |
| SCHEMBL12894051 | 0.75 | MAPT (0.39) | HSD17B10MAPTHPGDALDH1A1NPSR1 | |
| SCHEMBL12894058 | 0.74 | ALDH1A1 (0.38) | HSD17B10MAPTHPGDALDH1A1NPSR1 | |
| SCHEMBL10070043 | 0.73 | TSHR (0.35) | TSHRHSD17B10MAPTHPGDTAAR1 | |
| SCHEMBL10070066 | 0.72 | MAPT (0.37) | HSD17B10MAPTHPGDCNR2ALDH1A1 | |
| SCHEMBL10070425 | 0.72 | SYK (0.40) | TSHRHSD17B10MAPTHPGDTAAR1 | |
| SCHEMBL10070064 | 0.72 | HPGD (0.35) | TSHRHSD17B10MAPTHPGDTAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012006680-A1 | 7, 9-NITROGEN RADICAL-4-OXO-4H-PYRIDO[L,2-A]PYRIMIDINE-2-CARBOXYLIC ACID BENZYLAMIDE ANTI-VIRALS | AVEXA LIMITED (AU) | 2012-01-19 | — | — | WO | disclosed |