⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22750752 | 0.69 | — | — | |
| SCHEMBL1007070 | 0.68 | — | — | |
| SCHEMBL29560246 | 0.65 | TP53 (0.35) | — | |
| SCHEMBL17157136 | 0.61 | CSNK2A2 (0.40) | — | |
| SCHEMBL27458469 | 0.59 | — | — | |
| SCHEMBL30397495 | 0.58 | NOTUM (0.48) | — | |
| SCHEMBL30397118 | 0.58 | NOTUM (0.48) | — | |
| Ammonia Solution, Strong SCHEMBL28215040 | 0.58 | — | — | |
| SCHEMBL211365 | 0.57 | GSK3B (0.61) | — | |
| SCHEMBL28884749 | 0.57 | ALDH1A1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113185504-B | Furan-linked 1,3, 4-oxadiazole formamide compounds and preparation method and application thereof | 南京林业大学 | 2022-01-07 | — | — | CN | claimed |
| CN-113185504-A | Furan-linked 1,3, 4-oxadiazole formamide compounds and preparation method and application thereof | 南京林业大学 | 2021-07-30 | — | — | CN | claimed |
| CN-113185504-B | Furan-linked 1,3, 4-oxadiazole formamide compounds and preparation method and application thereof | 南京林业大学 | 2022-01-07 | — | — | CN | disclosed |
| CN-113185504-B | Furan-linked 1,3, 4-oxadiazole formamide compounds and preparation method and application thereof | 南京林业大学 | 2022-01-07 | — | — | CN | disclosed |
| CN-113185504-B | Furan-linked 1,3, 4-oxadiazole formamide compounds and preparation method and application thereof | 南京林业大学 | 2022-01-07 | — | — | CN | disclosed |
| CN-113214236-B | Preparation method of thiophene bi-1, 3, 4-oxadiazole formamide compounds, products and application thereof | 南京林业大学 | 2022-01-04 | — | — | CN | disclosed |
| CN-113214236-A | Preparation method of thiophene bi-1, 3, 4-oxadiazole formamide compounds, products and application thereof | 南京林业大学 | 2021-08-06 | — | — | CN | disclosed |
| CN-113185504-A | Furan-linked 1,3, 4-oxadiazole formamide compounds and preparation method and application thereof | 南京林业大学 | 2021-07-30 | — | — | CN | disclosed |
| CN-113185504-A | Furan-linked 1,3, 4-oxadiazole formamide compounds and preparation method and application thereof | 南京林业大学 | 2021-07-30 | — | — | CN | disclosed |
| CN-113185504-A | Furan-linked 1,3, 4-oxadiazole formamide compounds and preparation method and application thereof | 南京林业大学 | 2021-07-30 | — | — | CN | disclosed |
| CN-110022875-A | Therapeutic inhibiting compound | 莱福斯希医药公司 | 2019-07-16 | — | — | CN | disclosed |
| US-20120107273-A1 | NEW PIPERAZINE COMPOUND AND USE THEREOF AS A HCV POLYMERASE INHIBITOR | JAPAN TOBACCO INC. (JP) | 2012-05-03 | — | — | US | disclosed |
| US-8017612-B2 | therapeutic agent for hepatitis C; R)-4-(4-trifluoromethyl-benzenesulfonyl)-piperazine-1,3-dicarboxylic acid 3-(4-isopropyl-benzylamide) 1-pyridin-4-ylamide; enzyme inhibitors | JAPAN TOBACCO INC. (JP) | 2011-09-13 | — | — | US | disclosed |
| US-20110118236-A1 | HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-05-19 | — | — | US | disclosed |
| EP-2269990-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2011-01-05 | — | — | EP | disclosed |
| EP-2009004-A1 | NOVEL PIPERAZINE COMPOUND, AND USE THEREOF AS HCV POLYMERASE INHIBITOR | Japan Tobacco, Inc. (JP) | 2008-12-31 | — | — | EP | disclosed |
| US-20080081818-A1 | therapeutic agent for hepatitis C; R)-4-(4-trifluoromethyl-benzenesulfonyl)-piperazine-1,3-dicarboxylic acid 3-(4-isopropyl-benzylamide) 1-pyridin-4-ylamide; enzyme inhibitors | JAPAN TOBACCO INC. (JP) | 2008-04-03 | — | — | US | disclosed |