Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.40 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.40 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.40 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19755675 | 0.70 | KDM4E (0.43) | CSNK2A2CSNK2BCSNK2A1CSNK2A3MAPT | |
| SCHEMBL9312752 | 0.62 | CHRM2 (0.46) | MAPTMEN1POLBKMT2AL3MBTL1 | |
| SCHEMBL22750752 | 0.62 | — | — | |
| SCHEMBL1509976 | 0.62 | MEN1 (0.64) | MAPTMEN1POLBKMT2AL3MBTL1 | |
| SCHEMBL1007070 | 0.61 | — | — | |
| SCHEMBL25234778 | 0.60 | MEN1 (0.36) | MAPTMEN1POLBKMT2AL3MBTL1 | |
| SCHEMBL14746911 | 0.60 | NOTUM (0.31) | CSNK2A2CSNK2BCSNK2A1CSNK2A3 | |
| SCHEMBL8286810 | 0.59 | BCHE (0.61) | MAPTMEN1POLBKMT2AL3MBTL1 | |
| SCHEMBL708021 | 0.59 | TSHR (0.40) | MAPTMEN1POLBKMT2AL3MBTL1 | |
| SCHEMBL2639258 | 0.58 | ALDH1A1 (0.70) | MAPTMEN1POLBKMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9383360-B2 | Compositions and methods relating to lyme disease | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2016-07-05 | — | — | US | disclosed |
| US-20150293096-A1 | COMPOSITIONS AND METHODS RELATING TO LYME DISEASE | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES | 2015-10-15 | — | — | US | disclosed |