Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.35 |
| ▸ | PDE5A | O76074 | 2/20 | 0.32 |
| ▸ | PDE6A | P16499 | 2/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | GSK3A | P49840 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | NQO1 | P15559 | 1/20 | 0.30 |
| ▸ | NQO2 | P16083 | 1/20 | 0.30 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10070425 | 0.84 | SYK (0.40) | SYK | |
| SCHEMBL10069908 | 0.83 | KDM4E (0.32) | MAOAMAOB | |
| SCHEMBL10070091 | 0.77 | — | — | |
| SCHEMBL10070992 | 0.77 | TYK2 (0.31) | — | |
| SCHEMBL10071004 | 0.75 | — | — | |
| SCHEMBL10069924 | 0.72 | PDE4B (0.39) | PDE4BMAOB | |
| SCHEMBL10070928 | 0.71 | ESR1 (0.33) | MAOAMAOB | |
| SCHEMBL10069877 | 0.71 | THRA (0.34) | MAOAMAOB | |
| SCHEMBL10070427 | 0.71 | SYK (0.39) | SYK | |
| SCHEMBL10070944 | 0.70 | MMP9 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012006680-A1 | 7, 9-NITROGEN RADICAL-4-OXO-4H-PYRIDO[L,2-A]PYRIMIDINE-2-CARBOXYLIC ACID BENZYLAMIDE ANTI-VIRALS | AVEXA LIMITED (AU) | 2012-01-19 | — | — | WO | disclosed |