Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | FBP1 | P09467 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10071082 | 0.80 | KIF11 (0.56) | SMN1; SMN2HDAC3HDAC1KIF11ALDH1A1 | |
| SCHEMBL18475596 | 0.79 | KIF11 (0.54) | SMN1; SMN2HDAC3HDAC1KIF11ALDH1A1 | |
| SCHEMBL11990356 | 0.74 | IDO1 (0.52) | SMN1; SMN2KIF11LMNAKMT2AGAA | |
| SCHEMBL29562983 | 0.73 | KIF11 (0.47) | SMN1; SMN2KIF11ALDH1A1LMNAHPGD | |
| SCHEMBL20710206 | 0.72 | KIF11 (0.53) | SMN1; SMN2KIF11ALDH1A1LMNAPOLB | |
| SCHEMBL7268289 | 0.71 | KIF11 (0.67) | SMN1; SMN2KIF11ALDH1A1HPGDCYP1A2 | |
| SCHEMBL14078204 | 0.71 | KIF11 (0.79) | KIF11LMNACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL17980744 | 0.71 | KIF11 (0.52) | SMN1; SMN2KIF11ALDH1A1LMNAHPGD | |
| SCHEMBL10065919 | 0.70 | KIF11 (0.55) | SMN1; SMN2KIF11ALDH1A1LMNAKMT2A | |
| SCHEMBL29601869 | 0.70 | KIF11 (0.45) | HDAC3HDAC1KIF11ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120045393-A1 | LHRH-II PEPTIDE ANALOGS | BRACCO IMAGING SPA (IT) | 2012-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120045393-A1 | LHRH-II PEPTIDE ANALOGS | LHCGR, GNRHR, FSHR | SMN1; SMN2 3010/4885HDAC3 1327/4885HDAC1 1265/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.