⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10138045 | 0.82 | — | — | |
| SCHEMBL416419 | 0.78 | — | — | |
| SCHEMBL10310996 | 0.78 | — | — | |
| SCHEMBL10137999 | 0.76 | — | — | |
| SCHEMBL12731238 | 0.74 | HSD17B10 (0.30) | — | |
| SCHEMBL12133410 | 0.73 | — | — | |
| SCHEMBL13058167 | 0.72 | — | — | |
| SCHEMBL18104322 | 0.71 | ADRB2 (0.32) | — | |
| SCHEMBL10071214 | 0.71 | — | — | |
| SCHEMBL10019285 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230287034-A1 | CYCLIC DINUCLEOTIDES AS STING AGONISTS | JANSSEN BIOTECH INC (US) | 2023-09-14 | — | — | US | disclosed |
| US-20230146410-A1 | CYCLIC DINUCLEOTIDES AS STING AGONISTS | JANSSEN BIOTECH INC (US) | 2023-05-11 | — | — | US | disclosed |
| US-20160376585-A1 | OLIGONUCLEOTIDE-LIGAND CONJUGATES AND PROCESS FOR THEIR PREPARATION | BANK OF AMERICA, N.A. | 2016-12-29 | — | — | US | disclosed |
| US-20150191727-A1 | BICYCLIC CYCLOHEXOSE NUCLEIC ACID ANALOGS | ISIS PHARMACEUTICALS, INC. (US) | 2015-07-09 | — | — | US | disclosed |
| US-9012421-B2 | Bicyclic cyclohexose nucleic acid analogs | ISIS PHARMACEUTICALS, INC. (US) | 2015-04-21 | — | — | US | disclosed |
| US-8507455-B2 | Folate conjugates | ALNYLAM PHARMACEUTICALS, INC. (US) | 2013-08-13 | — | — | US | disclosed |
| US-20120172414-A1 | BICYCLIC CYCLOHEXOSE NUCLEIC ACID ANALOGS | ISIS PHARMACEUTICALS, INC. (US) | 2012-07-05 | — | — | US | disclosed |
| US-20120016128-A1 | Rhodamine lactone phosphoramidites and polymers | AAT BIOQUEST, INC. | 2012-01-19 | — | — | US | disclosed |
| US-20090247614-A1 | Folate Conjugates | ALNYLAM PHARMACEUTICALS, INC. (US) | 2009-10-01 | — | — | US | disclosed |