⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL383731 | 0.87 | TSHR (0.32) | — | |
| SCHEMBL4818972 | 0.85 | TSHR (0.31) | — | |
| SCHEMBL17133199 | 0.82 | — | — | |
| SCHEMBL10030503 | 0.80 | TSHR (0.35) | — | |
| SCHEMBL566248 | 0.80 | TSHR (0.31) | — | |
| SCHEMBL16504168 | 0.80 | TSHR (0.30) | — | |
| SCHEMBL14136628 | 0.80 | TSHR (0.30) | — | |
| SCHEMBL2621446 | 0.80 | TSHR (0.30) | — | |
| SCHEMBL22743731 | 0.79 | — | — | |
| SCHEMBL22743730 | 0.79 | NLRP3 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230332197-A1 | NUCLEOSIDES AND NUCLEOTIDES WITH 3' VINYL BLOCKING GROUP | ILLUMINA, INC. | 2023-10-19 | — | — | US | disclosed |
| US-9783562-B2 | Phytosphingosine-1-phosphate derivative, preparation method therefor, and composition for preventing and treating hair loss or for growing hair comprising same | PHYTOS CO., LTD (KR) | 2017-10-10 | — | — | US | disclosed |
| US-20160046656-A1 | NOVEL PHYTOSPHINGOSINE-1-PHOSPHATE DERIVATIVE, PREPARATION METHOD THEREFOR, AND COMPOSITION FOR PREVENTING AND TREATING HAIR LOSS OR FOR GROWING HAIR COMPRISING SAME | PHYTOS CO., LTD. (KR) | 2016-02-18 | — | — | US | disclosed |
| US-20150080457-A1 | 5' PHOSPHATE MIMICS | BANK OF AMERICA, N.A. | 2015-03-19 | — | — | US | disclosed |
| US-8927513-B2 | 5′ phosphate mimics | ALNYLAM PHARMACEUTICALS, INC. (US) | 2015-01-06 | — | — | US | disclosed |
| US-20120157511-A1 | 5' PHOSPHATE MIMICS | ALNYLAM PHARMACEUTICALS, INC. (US) | 2012-06-21 | — | — | US | disclosed |
| US-8173198-B2 | Deposition of metal oxides onto surfaces as an immobilization vehicle for carboxylated or phophated particles or polymers | Life Technologies Corporation (US) | 2012-05-08 | — | — | US | disclosed |
| US-20110159305-A1 | Intermediates And Methods For Forming Passivated Surfaces On Oxide Layers And Articles Produced Thereby | APPLIED BIOSYSTEMS, LLC (US) | 2011-06-30 | — | — | US | disclosed |
| US-20100086927-A1 | DEPOSITION OF METAL OXIDES ONTO SURFACES AS AN IMMOBILIZATION VEHICLE FOR CARBOXYLATED OR PHOPHATED PARTICLES OR POLYMERS | Life Technologies Corporation (US) | 2010-04-08 | — | — | US | disclosed |
| US-20080176761-A1 | Intermediates and Methods for Forming Passivated Surfaces on Oxide Layers and Articles Produced Thereby | APPLERA CORPORATION, APPLIED BIOSYSTEMS GROUP (US) | 2008-07-24 | — | — | US | disclosed |