Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.58 |
| ▸ | AXL | P30530 | 1/20 | 0.56 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.50 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.48 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.48 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.48 |
| ▸ | KIF20A | O95235 | 1/20 | 0.48 |
| ▸ | CLK1 | P49759 | 1/20 | 0.48 |
| ▸ | CLK2 | P49760 | 1/20 | 0.48 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.48 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.48 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | CDK2 | P24941 | 3/20 | 0.44 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.44 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14319054 | 0.79 | MAP2K1 (0.57) | MAP2K1AXLGPR84CDK5CDK5R1 | |
| SCHEMBL29468201 | 0.79 | MAP2K1 (0.71) | MAP2K1AXLGPR84CDK5CDK5R1 | |
| SCHEMBL27708260 | 0.79 | MAP2K1 (0.71) | MAP2K1AXLGPR84CDK5CDK5R1 | |
| SCHEMBL985214 | 0.79 | MAP2K1 (0.71) | MAP2K1AXLGPR84CDK5CDK5R1 | |
| SCHEMBL20757915 | 0.77 | MAP2K1 (0.52) | MAP2K1AXLGPR84CDK5CDK5R1 | |
| Hydrochloric Acid SCHEMBL3608101 | 0.77 | MAP2K1 (0.69) | MAP2K1AXLGPR84CDK5CDK5R1 | |
| SCHEMBL19675367 | 0.76 | MAP2K1 (0.62) | MAP2K1AXLGPR84CDK5CDK5R1 | |
| SCHEMBL12647233 | 0.76 | MAP2K1 (0.67) | MAP2K1AXLGPR84CDK5CDK5R1 | |
| SCHEMBL2991525 | 0.76 | MAP2K1 (0.71) | MAP2K1AXLGPR84CDK5CDK5R1 | |
| SCHEMBL3608096 | 0.76 | MAP2K1 (0.67) | MAP2K1AXLGPR84CDK5CDK5R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110118236-A1 | HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-05-19 | — | — | US | disclosed |
| EP-2269990-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2011-01-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110118236-A1 | HETEROCYCLIC COMPOUND | GRIN1, GRM1, GRIK1 | MAP2K1 3493/4885AXL 546/4885GPR84 86/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.