SCHEMBL1007160

SCHEMBL1007160

O=C(O)CCc1ccc(I)cc1

nearest known ligand 0.71

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 14/20 0.65
KEAP1 Q14145 1/20 0.64
FFAR4 Q5NUL3 4/20 0.55
CA1 P00915 1/20 0.55
CA2 P00918 1/20 0.55
LMNA P02545 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
P4HTM Q9NXG6 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL69746 0.88 FFAR1 (0.81) FFAR1KEAP1FFAR4CA1CA2
SCHEMBL452845 0.87 SMN1; SMN2 (0.67) FFAR1KEAP1LMNA
Hydrochloric Acid SCHEMBL25264643 0.85 FFAR1 (0.77) FFAR1KEAP1FFAR4CA1CA2
SCHEMBL2197174 0.85 MAPT (0.66) FFAR1LMNA
SCHEMBL27864939 0.84 F2RL1 (0.47) FFAR1KEAP1L3MBTL1
SCHEMBL9860436 0.84 MAPT (0.69) FFAR1
SCHEMBL2835656 0.84 MAPT (0.69) FFAR1
Iocanlidic Acid SCHEMBL290025 0.84 MAPT (0.69) FFAR1
SCHEMBL25575670 0.84 MAPT (0.69) FFAR1
SCHEMBL6926013 0.82 FFAR1 (0.65) FFAR1KEAP1FFAR4CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 260 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120137643-A Composite material, preparation method thereof, photoelectric device and display device 广东聚华新型显示研究院 2025-06-13 CN claimed
US-20240050599-A1 TRIFUNCTIONAL CONSTRUCTS WITH TUNABLE PHARMACOKINETICS USEFUL IN IMAGING AND ANTI-TUMOR THERAPIES CORNELL UNIVERSITY (US) 2024-02-15 US claimed
US-20230285603-A1 TRIFUNCTIONAL CONSTRUCTS WITH TUNABLE PHARMACOKINETICS USEFUL IN IMAGING AND ANTI-TUMOR THERAPIES CORNELL UNIVERSITY (US) 2023-09-14 US claimed
US-20230165979-A1 COPPER-CONTAINING THERAGNOSTIC COMPOSITIONS AND METHODS OF USE CORNELL UNIVERSITY (US) 2023-06-01 US claimed
CN-115989042-A Copper-containing theranostic compounds and methods of use 康奈尔大学 2023-04-18 CN claimed
EP-4146236-A1 COPPER-CONTAINING THERAGNOSTIC COMPOUNDS AND METHODS OF USE Cornell University (US) 2023-03-15 EP claimed
WO-2021225760-A1 COPPER-CONTAINING THERAGNOSTIC COMPOUNDS AND METHODS OF USE CORNELL UNIVERSITY (US) 2021-11-11 WO claimed
US-20210121584-A1 TRIFUNCTIONAL CONSTRUCTS WITH TUNABLE PHARMACOKINETICS USEFUL IN IMAGING AND ANTI-TUMOR THERAPIES CORNELL UNIVERSITY (US) 2021-04-29 US claimed
US-20200405888-A1 TRIFUNCTIONAL CONSTRUCTS WITH TUNABLE PHARMACOKINETICS USEFUL IN IMAGING AND ANTI-TUMOR THERAPIES CORNELL UNIVERSITY (US) 2020-12-31 US claimed
US-10806806-B2 Trifunctional constructs with tunable pharmacokinetics useful in imaging and anti-tumor therapies CORNELL UNIVERSITY (US) 2020-10-20 US claimed
US-20190015531-A1 TRIFUNCTIONAL CONSTRUCTS WITH TUNABLE PHARMACOKINETICS USEFUL IN IMAGING AND ANTI-TUMOR THERAPIES CORNELL UNIVERSITY 2019-01-17 US claimed
US-RE37303-E1 Imidazole compounds and their therapeutic applications INSTITUT NATIONAL DEL LA SANTE ET DE LA RECHERCHE MEDICALE (FR) 2001-07-31 US claimed
EP-0597088-B1 NOVEL IMIDAZOLE DERIVATIVES, THEIR PREPARATION AND THERAPEUTIC APPLICATIONS INST NAT SANTE RECH MED (FR) 2000-12-06 EP claimed
US-5708171-A HISTAMINE H3-RECEPTOR ANTAGONIST INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) 1998-01-13 US claimed
US-20260091008-A1 DOUBLE TARGETED CONSTRUCTS TO AFFECT TUMOR KILL CORNELL UNIVERSITY (US) 2026-04-02 US disclosed
EP-4713096-A1 CDK INHIBITOR COMPOUNDS Aleksia Therapeutics, Inc. (US) 2026-03-25 EP disclosed
EP-4695271-A2 A CYCLIC PEPTIDE FOR TRAPPING INTERLEUKIN-1 BETA Merck Sharp & Dohme LLC (US) 2026-02-18 EP disclosed
EP-0595635-A1 Alpha-phosphorous substituted sulfonate derivatives as squalene synthetase inhibitors E.R. Squibb & Sons, Inc. (US) 1994-05-04 EP disclosed
EP-0438233-A2 Orally active renin inhibitors PFIZER INC. (US) 1991-07-24 EP disclosed
US-4252719-A REMOVAL OF A TERTIARY HYDROGEN FROM A 5-A-STEROID BY CHLORINATING THE STEROID BEING FIRST ESTERIFIED BY AN IODOARYL-CONTAINING ESTERIFICATION AGENT RESEARCH CORPORATION (US) 1981-02-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210121584-A1 TRIFUNCTIONAL CONSTRUCTS WITH TUNABLE PHARMACOKINETICS USEFUL IN IMAGING AND ANTI-TUMOR THERAPIES VHL, GLS, GPER1 FFAR1 1717/4885KEAP1 1205/4885FFAR4 1201/4885
US-20260091008-A1 DOUBLE TARGETED CONSTRUCTS TO AFFECT TUMOR KILL PSMA2, CD47, KLK3 FFAR1 1436/4885KEAP1 4104/4885FFAR4 2935/4885
US-20230285603-A1 TRIFUNCTIONAL CONSTRUCTS WITH TUNABLE PHARMACOKINETICS USEFUL IN IMAGING AND ANTI-TUMOR THERAPIES VHL, GLS, GPER1 FFAR1 1717/4885KEAP1 1205/4885FFAR4 1201/4885
US-20240050599-A1 TRIFUNCTIONAL CONSTRUCTS WITH TUNABLE PHARMACOKINETICS USEFUL IN IMAGING AND ANTI-TUMOR THERAPIES VHL, GLS, GPER1 FFAR1 1717/4885KEAP1 1205/4885FFAR4 1201/4885
US-20200405888-A1 TRIFUNCTIONAL CONSTRUCTS WITH TUNABLE PHARMACOKINETICS USEFUL IN IMAGING AND ANTI-TUMOR THERAPIES VHL, GLS, GPER1 FFAR1 1717/4885KEAP1 1205/4885FFAR4 1201/4885
US-10806806-B2 Trifunctional constructs with tunable pharmacokinetics useful in imaging and anti-tumor therapies VHL, GLS, GPER1 FFAR1 1717/4885KEAP1 1205/4885FFAR4 1201/4885
US-20230165979-A1 COPPER-CONTAINING THERAGNOSTIC COMPOSITIONS AND METHODS OF USE SHBG, FABP6, SERPINA6 FFAR1 2787/4885KEAP1 449/4885FFAR4 3399/4885
US-20190015531-A1 TRIFUNCTIONAL CONSTRUCTS WITH TUNABLE PHARMACOKINETICS USEFUL IN IMAGING AND ANTI-TUMOR THERAPIES VHL, GLS, GPER1 FFAR1 1717/4885KEAP1 1205/4885FFAR4 1201/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.