SCHEMBL10071738

SCHEMBL10071738

O=C1c2ccccc2Cc2c1ccc1ccccc21

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAOA P21397 2/20 0.57
▸ ALDH1A1 P00352 6/20 0.50
▸ SMN1; SMN2 Q16637 3/20 0.50
▸ MAPT P10636 2/20 0.50
▸ KDM4E B2RXH2 2/20 0.50
▸ MEN1 O00255 1/20 0.50
▸ NPC1 O15118 1/20 0.50
▸ RAB9A P51151 1/20 0.50
▸ KMT2A Q03164 1/20 0.50
▸ CES1 P23141 2/20 0.48
▸ BCHE P06276 1/20 0.48
▸ DNMT1 P26358 1/20 0.47
▸ HTT P42858 2/20 0.44
▸ LMNA P02545 1/20 0.44
▸ NPSR1 Q6W5P4 1/20 0.44
▸ AKR1B1 P15121 1/20 0.43
▸ ANPEP P15144 1/20 0.43
▸ CYP1A2 P05177 2/20 0.42
▸ CYP2C19 P33261 2/20 0.42
▸ HPGD P15428 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzo(A)Fluorene SCHEMBL29432662 0.85 CA1 (0.46) MAOAALDH1A1SMN1; SMN2MAPTKDM4E
Benzo(A)Fluorene SCHEMBL29620372 0.85 CA1 (0.46) MAOAALDH1A1SMN1; SMN2MAPTKDM4E
Benzo(A)Fluorene SCHEMBL29413802 0.85 CA1 (0.46) MAOAALDH1A1SMN1; SMN2MAPTKDM4E
Benzo(A)Fluorene SCHEMBL150250 0.85 CA1 (0.46) MAOAALDH1A1SMN1; SMN2MAPTKDM4E
Anthrone SCHEMBL29089221 0.80 MAOA (0.69) MAOAALDH1A1SMN1; SMN2MAPTKDM4E
SCHEMBL14490515 0.77 DNMT1 (0.44) ALDH1A1SMN1; SMN2KDM4EMEN1KMT2A
SCHEMBL2486633 0.77 HPRT1 (0.50) ALDH1A1SMN1; SMN2MAPTKDM4EMEN1
SCHEMBL31199126 0.77 HPRT1 (0.50) ALDH1A1SMN1; SMN2MAPTKDM4EMEN1
SCHEMBL4852395 0.76 ALDH1A1 (0.49) ALDH1A1KDM4EBCHELMNAANPEP
SCHEMBL23839 0.76 MAOA (0.57) MAOAALDH1A1SMN1; SMN2MAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8092872-B2 Optical film, antireflection film, and polarizing plate and display device using the same FUJIFILM CORPORATION (JP) 2012-01-10 — — US disclosed
US-8092872-B2 Optical film, antireflection film, and polarizing plate and display device using the same FUJIFILM CORPORATION (JP) 2012-01-10 — — US disclosed
US-7785676-B2 Optical compensation sheet, polarizing plate, and liquid crystal display device FUJIFILM CORPORATION (JP) 2010-08-31 — — US disclosed
US-7785676-B2 Optical compensation sheet, polarizing plate, and liquid crystal display device FUJIFILM CORPORATION (JP) 2010-08-31 — — US disclosed
US-20090122233-A1 OPTICAL COMPENSATION SHEET, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2009-05-14 — — US disclosed
US-20090122233-A1 OPTICAL COMPENSATION SHEET, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2009-05-14 — — US disclosed
US-20080131674-A1 OPTICAL FILM, ANTIREFLECTION FILM, AND POLARIZING PLATE AND DISPLAY DEVICE USING THE SAME FUJIFILM CORPORATION (JP) 2008-06-05 — — US disclosed
US-20080131674-A1 OPTICAL FILM, ANTIREFLECTION FILM, AND POLARIZING PLATE AND DISPLAY DEVICE USING THE SAME FUJIFILM CORPORATION (JP) 2008-06-05 — — US disclosed
WO-2007049814-A1 OPTICAL COMPENSATION SHEET, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2007-05-03 — — WO disclosed
Send feedback