SCHEMBL10071757

SCHEMBL10071757

CCC(CCCO)C(C)(C)c1ccc(O)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 13/20 0.40
ESR2 Q92731 11/20 0.40
CYP3A4 P08684 4/20 0.39
LMNA P02545 2/20 0.39
AR P10275 2/20 0.39
SLC6A2 P23975 2/20 0.39
SLC6A3 Q01959 2/20 0.39
TYR P14679 1/20 0.39
HPGD P15428 1/20 0.39
TSHR P16473 1/20 0.39
SLC6A4 P31645 1/20 0.39
HTR6 P50406 1/20 0.39
ESRRG P62508 1/20 0.39
HSD17B10 Q99714 1/20 0.39
SHBG P04278 1/20 0.38
CYP1A2 P05177 1/20 0.36
PGR P06401 1/20 0.36
CHRM2 P08172 1/20 0.36
ADORA3 P0DMS8 1/20 0.36
CYP2D6 P10635 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10071985 0.89 ESR1 (0.42) ESR1ESR2CYP3A4LMNAAR
SCHEMBL27980865 0.78 ESR1 (0.50) ESR1ESR2CYP3A4LMNAAR
SCHEMBL17341747 0.75 ESR1 (0.49) ESR1ESR2CYP3A4LMNAAR
SCHEMBL1823104 0.71 TSHR (0.38) LMNATSHRHSD17B10ALDH1A1MEN1
Bisphenol A SCHEMBL28078248 0.71 ESR1 (0.55) ESR1ESR2CYP3A4LMNAAR
SCHEMBL7202909 0.71 ESR1 (0.48) ESR1ESR2CYP3A4LMNAAR
SCHEMBL6302501 0.70 ESR1 (0.46) ESR1ESR2CYP3A4LMNAAR
SCHEMBL31320383 0.70 PTGS2 (0.46) CYP3A4
SCHEMBL31544989 0.70 PTGS2 (0.46) CYP3A4
SCHEMBL14490602 0.70 ESR1 (0.49) ESR1ESR2CYP3A4LMNAAR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2143750-B1 Aromatic polycarbonate composition, process for producing the same, and hollow container therefrom MITSUBISHI CHEM CORP (JP) 2012-06-27 EP disclosed