Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 14/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 11/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | TYR | P14679 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | ESRRG | P62508 | 1/20 | 0.38 |
| ▸ | SHBG | P04278 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.36 |
| ▸ | TACR2 | P21452 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10071757 | 0.89 | ESR1 (0.40) | ESR1ESR2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL27980865 | 0.83 | ESR1 (0.50) | ESR1ESR2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7608542 | 0.81 | MEN1 (0.35) | LMNAALDH1A1HIF1AMEN1KMT2A | |
| SCHEMBL7005030 | 0.77 | ESR1 (0.51) | ESR1ESR2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8064735 | 0.74 | ESR1 (0.47) | ESR1ESR2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL13068596 | 0.74 | MME (0.44) | ESR1ESR2SLC6A2SLC6A3CYP3A4 | |
| SCHEMBL7603499 | 0.73 | LMNA (0.41) | LMNAHSD17B10TSHRALDH1A1MEN1 | |
| SCHEMBL7605249 | 0.73 | LMNA (0.41) | LMNAHSD17B10TSHRALDH1A1MEN1 | |
| SCHEMBL6302501 | 0.73 | ESR1 (0.46) | ESR1ESR2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL31320421 | 0.72 | PTGS2 (0.46) | CYP3A4PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2143750-B1 | Aromatic polycarbonate composition, process for producing the same, and hollow container therefrom | MITSUBISHI CHEM CORP (JP) | 2012-06-27 | — | — | EP | disclosed |